3'-o-tert-butyldimethylsilyl-5'-o-dmt-uridine suppliers USA
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It is used for special nucleoside or RNA modification. Synonyms: 5'-DMT-3'-tBDSilyl Uridine; 5'-O-DMT-3'-O-TBDMS uridine; 5'-O-(4,4'-Dimethoxytrityl)-3'-O-t-butyldimethylsilyl uridine; 3'-O-(tert-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)uridine; 1-((2R,3R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-3-hydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]uridine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine. Grade: ≥95%. CAS No. 81246-81-3. Molecular formula: C36H44N2O8Si. Mole weight: 660.83.
5'-O-DMT-3'-O-tert-Butyldimethylsilyl-uridine-2'-CE phosphoramidite is a phosphoramidite reagent used in the synthesis of oligonucleotides. It features a dimethoxytrityl (DMT) protecting group at the 5'-hydroxyl position, a tert-butyldimethylsilyl (TBDMS) protecting group at the 3'-hydroxyl position, and a cyanoethyl (CE) protecting group on the phosphoramidite at the 2' position. These protective groups ensure efficient incorporation of uridine into oligonucleotides while enhancing the stability and accuracy of synthesis. This reagent is important for creating modified oligonucleotides for research and therapeutic applications. Synonyms: 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine 2'-CE phosphoramidite; 3'-TBDMS-rU Phosphoramidite; 5-O-(4,4'-dimethoxytrityl)-2-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-3-O-(tert-butyl-dimethyl-silyl)-1-deoxy-1-uracil-1-yl-beta-D-ribo-pentofuranose; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 3'-OTBS U 2'-amidite; 3'-O-TBDMS-5'-O-DMT-rU CED phosphoramidite; DMT-3'-O-TBDMS-U-2'-CE-Phosphoramidite. Grade: ≥97% by HPLC. CAS No. 129451-77-0. Molecular formula: C45H61N4O9PSi. Mole weight: 861.05.
2'-O-Tert-butyldimethylsilyl-5'-O-DMT-uridine
It is used for RNA synthesis and special nucleoside modification. Synonyms: 5'-DMT-2'-tBDSilyl Uridine; 5'-O-DMT-2'-O-TBDMS uridine; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-t-butyldimethylsilyl uridine; 1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 2'-O-(tert-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)uridine; 5'-O-(4,4'-Dimethoxytrityl) 2'-O-[(1,1-dimethylethyl)-dimethylsilyl]-uridine. Grade: ≥95%. CAS No. 81246-80-2. Molecular formula: C36H44N2O8Si. Mole weight: 660.83.
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