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Used in the preparation of biarylpyrazole based derivatives as cannabinoid CB1 receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 221385-24-6. Pack Sizes: 25mg. US Biological Life Sciences.
1-(4-Methoxyphenyl)-3-(4-nitrophenyl)-1H-pyrazole-4-carbaldehyde. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SALOR-INT L321184-1EA;1-(4-METHOXYPHENYL)-3-(4-NITROPHENYL)-1H-PYRAZOLE-4-CARBALDEHYDE. Product Category: Heterocyclic Organic Compound. CAS No. 618101-68-1. Molecular formula: C17H13N3O4. Mole weight: 323.3. Product ID: ACM618101681. Alfa Chemistry ISO 9001:2015 Certified.
A cell-permeable diphenylpyrazolo compound that disrupts HIV accessary protein Nef dimerization (IC50 = 3uM in HEK293T cells) and prevents Nef-mediated Src family kinase Hck activation (IC50 = 2.8uM) without directly affecting the catalytic activity of c-Src, Hck, Lck, or Lyn. Shown to suppress HIV and SIV viral replication (IC50/strain/culture = 1uM/SIV deltaB670/CEM-174 and <0.3uM/HIV-1 NL4-3/CEM-T4) and infectivity, being ineffective against the replication of Nef-defective HIV-1 mutant. Molecular docking and in vitro binding studies reveal a high-affinity B9-targeting site formed at the Nef dimerization interface and a low-affinity binding site on each Nef monomer at the dimer interface periphery. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??ClN?O?S, Primary Target: Nef. US Biological Life Sciences.
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3-(1-(4-Nitrophenyl)-1H-pyrazol-5-yl)pyridine
3-(1-(4-Nitrophenyl)-1H-pyrazol-5-yl)pyridine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-(1-(4-nitrophenyl)-1H-pyrazol-5-yl)pyridine, ACN-000495, AK139640, 1269291-88-4. Product Category: Heterocyclic Organic Compound. CAS No. 1269291-88-4. Molecular formula: C14H10N4O2. Mole weight: 266.254800 [g/mol]. Purity: 0.96. IUPACName: 3-[2-(4-nitrophenyl)pyrazol-3-yl]pyridine. Canonical SMILES: C1=CC(=CN=C1)C2=CC=NN2C3=CC=C(C=C3)[N+](=O)[O-]. Product ID: ACM1269291884. Alfa Chemistry ISO 9001:2015 Certified.
3-Methyl-1-(4-nitrophenyl)-1H-pyrazol-5-amine
3-Methyl-1-(4-nitrophenyl)-1H-pyrazol-5-amine. Group: Biochemicals. Grades: Reagent Grade. CAS No. 16459-47-5. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
3-tert-Butyl-1-(4-nitrophenyl)-1H-pyrazol-5-amine
3-tert-Butyl-1-(4-nitrophenyl)-1H-pyrazol-5-amine. Group: Biochemicals. Alternative Names: 5-tert-Butyl-2-(4-nitrophenyl)-2H-pyrazol-3-ylamine. Grades: Highly Purified. CAS No. 251658-55-6. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences.