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(2S,4R)-4-methylglutamate (Kainate Receptor Agonsit, (2S,4R)-4-methylglutamate, SYM 2081) A potent agonist highly selective for kainate receptors over AMPA receptors (EC50 = 0.06-0.38uM and 132-453uM for kainate and AMPA receptors, respectively). Useful for distinguishing the functional roles played by kainate and AMPA receptors in neurotransmissions. Group: Biochemicals. Grades: Highly Purified. CAS No. 31137-74-3. Pack Sizes: 1mg. Molecular Formula: C?H??NO?. US Biological Life Sciences. USBiological 4
Worldwide
(2S,4R)-4-Methylglutamic acid (2S,4R)-4-Methylglutamic acid. Group: Biochemicals. Alternative Names: (4R)- 4-Methyl-L-glutamic Acid. Grades: Highly Purified. CAS No. 31137-74-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C6H11NO4. US Biological Life Sciences. USBiological 8
Worldwide
SYM 2081 SYM 2081 is a highly selective and potent kainate receptor agonist with IC50 for 35 nM, which is almost 200- and 3,000-fold selectivity over NMDA and AMPA receptors respectively. It also selectively inhibits the cloned excitatory amino acid transporter EAAT2 at higher concentrations. Synonyms: SYM2081; SYM-2081; SYM 2081; (2S,4R)-Me-Glu. (2S,4R)-4-Methylglutamic Acid; (4R)- 4-Methyl-L-glutamic Acid; erythro-L-4-Methylglutamic Acid; L-erythro-γ-Methylglutamic Acid; (2S,4R)-2-amino-4-methylpentanedioate. Grades: ≥97% by HPLC. CAS No. 31137-74-3. Molecular formula: C6H11NO4. Mole weight: 161.16. BOC Sciences 9

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