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| Product | Description | |
|---|---|---|
| RS-1 | High affinity RAD51 activator (Kd range = 48-107nM, value depends on cofactors present). Enhances homologous recombination activity of hRAD51. Enhances homology-directed repair and increases CRISPR-mediated knock-in efficiencies in vitro and in vivo.RS-1 is an activator of DNA repair protein RAD51 (Kd = 48-107 for human RAD51 with different cofactors present).1 It stimulates homologous strand assimilation activity at least 5- to 11-old, enhancing homologous recombination activity of hRAD51.1 RS-1 is a potent enhancer of CRISPR-mediated genome editing, increasing homology directed repair 3- to 6-fold.2 It is used to increase CRISPR-mediated knock-in efficiencies in vitro and in vivo.3,2,4. Group: Biochemicals. Alternative Names: 4-Bromo-N- (4-bromophenyl) -3- [ [ (phenylmethyl) amino] sulfonyl] benzamide. Grades: Highly Purified. CAS No. 312756-74-4. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C??H??Br?N?O?S, Molecular Weight: 524.23. US Biological Life Sciences. |  Worldwide |
| RS-1 | RS-1, a cell-permeable sulfonamido-benzamide compound that increases the DNA binding activity of RAD51 (Kd range = 48-107 nM, value depends on cofactors present). Synonyms: RS-1; RS 1; RS1. RAD51-Stimulatory Compound-1. 3-(benzylsulfamoyl)-4-bromo-N-(4-bromophenyl)benzamide3-((benzylamino)sulfonyl)-4-bromo-N-(4-bromophenyl)benzamideRS-1 compound. CAS No. 312756-74-4. Molecular formula: C20H16Br2N2O3S. Mole weight: 524.23. |  |
| RS-1 | RS-1 is a RAD51 activator, and also increases CRISPR/Cas9 -mediated knock-in efficiencies. Uses: Scientific research. Group: Signaling pathways. CAS No. 312756-74-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19793. |  |
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