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100mg Pack Size. Group: Bioactive Small Molecules. Formula: C29H32O13. CAS No. 33419-42-0. Prepack ID 12487027-100mg. Molecular Weight 588.56. See USA prepack pricing.
Etoposide
An antitumor agent. A topoisomerase II inhibitor. A derivative of podophyllotoxin that has major activity against a number of tumors, including germ cell neoplasms, small cell lung cancer, and malignant lymphoma. Induces apoptosis in human T cells, mouse thymocytes, and HL-60 human leukemia cells. Group: Biochemicals. Alternative Names: 4?-De methyl epipodophyllotoxin; 9-(4,6-O-ethylidene- β-D-glucopyranoside); (5R,5aR,8aR,9S)-9-[[4,6-O-(1R)-Ethylidene- β -D-glucopyranosyl]oxy]-5, 8, 8a, 9-tetrahydro-5- (4-hydroxy-3, 5-dimethoxyphenyl) furo[3, 4: 6, 7]naphtho[2, 3-d]-1, 3-dioxol-6 (5aH) -one; EPEG; VP 16-213; VePesid; Vepesid J; Zuyeyidal; trans-Etoposide. Grades: Highly Purified. CAS No. 33419-42-0. Pack Sizes: 100mg, 250mg, 500mg. Molecular Formula: C??H??O??, Molecular Weight: 588.56. US Biological Life Sciences.
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Etoposide
Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent. Etoposide inhibits topoisomerase II , thus stopping DNA replication. Etoposide induces cell cycle arrest, apoptosis and autophagy [1]. Uses: Scientific research. Group: Natural products. Alternative Names: VP-16; VP-16-213. CAS No. 33419-42-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-13629.
Etoposide
Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent. Etoposide inhibits topoisomerase II, thus stopping DNA replication. Etoposide induces cell cycle arrest, apoptosis and autophagy. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-Demethylepipodophyllotoxin-beta-d-ethylideneglucoside. Product Category: Inhibitors. Appearance: Powder. CAS No. 33419-42-0. Molecular formula: C29H32O13. Mole weight: 588.56. Purity: 0.98. IUPACName: (5S,5aR,8aR,9R)-5-[[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one. Canonical SMILES: CC1OCC2C(O1)C(C(C(O2)OC3C4COC(=O)C4C(C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)O)OC)O)O. Density: 1.29 g/ml. Product ID: ACM33419420. Alfa Chemistry ISO 9001:2015 Certified.
Potent anti-cancer compound. Induces apoptosis in normal and tumor cell lines. DNA Topoisomerase II activity inhibitor. Increases Topo II-mediated DNA breakage primarily by inhibiting the ability of the enzyme to religate cleaved nucleic acid molecules. Does not lead to immediate block of DNS synthesis, induces a progressive inhibition of DNA replication. p53 activator. Blocks the cell cycle between the end of the S phase and the early G2 phase. Oncoprotein Mdm2 synthesis inhibitor. Apoptosis inducer through the cytochrome c/Apaf-1/caspase-9 pathway and the Fas-mediated death signaling pathway. Cell cycle checkpoint activator. Affects gene expression at different levels (chromatin remodeling, transcrip- tion and alternative splicing). Chemotherapeutic compound used in cancers. Used in conditioning regimen prior to a bone marrow or blood stem cell transplantation. Highly effective in mobilizing stem cells. Group: Biochemicals. Alternative Names: 4-Des methyl epipodophyllotoxin; VP-16-213, NSC 141540. Grades: USP. CAS No. 33419-42-0. Pack Sizes: 250mg, 1g, 5g, 25g. US Biological Life Sciences.
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