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AS601245 AS601245 is a JNK Inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. Synonyms: AS601245; AS-601245; AS 601245. Grades: >98%. CAS No. 345987-15-7. Molecular formula: C20H16N6S. Mole weight: 372.45. BOC Sciences 2
AS601245 Cell-permeable. AS601245 is a potent, ATP-competitive JNK inhibitor (hJNK1: IC50=150nm, hJNK2: IC50=220nm and hJNK3: IC50=70nm). Displays anti-inflammatory properties and has been shown to reduce TNF-a plasma levels induced by LPS in mice. Group: Biochemicals. Alternative Names: (Z) -2- (Benzo[d]thiazol-2 (3H) -ylidene) -2- (2- ( (- (pyridine-3-yl) ethyl) amino) pyridine-4-yl) acetonitrile. Grades: Highly Purified. CAS No. 345987-15-7. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. USBiological 4
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