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5'-Ethyl carboxamidoadenosine 5'-Ethyl carboxamidoadenosine. Group: Biochemicals. Alternative Names: 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-b-D-ribofuranuronamide; NECA. Grades: Highly Purified. CAS No. 35920-39-9. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C12H16N6O4. US Biological Life Sciences. USBiological 8
Worldwide
5'-Ethylcarboxamido-adenosine 5'-Ethylcarboxamido-adenosine, a remarkable biomedicine, exhibits its prowess in cancer therapeutics. This extraordinary compound operates as an adenosine receptor agonist, effectively restraining the proliferation of malignant cells while orchestrating apoptosis. Uses: Vasodilator agents. Synonyms: NECA; 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-b-D-ribofuranuronamide; 5'-Ethylcarboxamido-D-adenosine. Grades: ≥ 95% by HPLC. CAS No. 35920-39-9. Molecular formula: C12H16N6O4. Mole weight: 308.29. BOC Sciences 2
Adenosine Receptor Agonist, NECA ( (2S, 3S, 4R, 5R) -5- (6-amino-9H-purin-9-yl) -N-ethyl-3, 4-di hydroxytetra hydrofuran-2-carboxamide ) A cell-permeable adenosine analog that acts a potent non-selective agonist of adenosine receptors (Ki = 14nM, 20nM, 2.4uM and 6.2nM for A1, A2A, A2B, A3, respectively). Increases intracellular cAMP production (EC50 = 3.1uM in A2B expressing CHO cells). Shown to increase glucagon release in a dose-dependent manner and inhibit insulin release at low concentrations. Although at higher concentration some insulin release is observed. Also, displays a wide range adenosine-dependent effects, such as blocking platelet aggregation and inhibiting DNA synthesis. When administered at reperfusion, it is shown reduce infarction and block the formation of the mitochondrial permeability transition pore by activating p70S6 kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 35920-39-9. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide
NECA NECA. Group: Biochemicals. Grades: Purified. CAS No. 35920-39-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide

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