362 07 2 Suppliers USA
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Product | Description | |
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2-Methoxy 17b-estradiol Quick inquiry Where to buy Suppliers range | 2-Methoxy 17b-estradiol. Group: Biochemicals. Alternative Names: (17b)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol; 2-Hydroxyestradiol 2-methyl ether; 2-Methoxyestra-1,3,5(10)-triene-3,17b-diol. Grades: Highly Purified. CAS No. 362-07-2. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C19H26O3. US Biological Life Sciences. | Worldwide |
2-methoxyestradiol Quick inquiry Where to buy Suppliers range | 2-methoxyestradiol, also known as 2-ME, is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing endothelial cell proliferation and inducing endothelial cell apoptosis. This agent also inhibits tumor cell growth by binding to tubulin, resulting in antimitotic activity, and by inducing caspase activation, resulting in cell cycle arrest in the G2 phase, DNA fragmentation, and apoptosis. Uses: Antineoplastic agents. Synonyms: 2-ME; 2-Methoxy Estradiol. US brand name: Panzem. Abbreviation: 2ME2. Chemical structure name: (17beta)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol. Grades: 0.98. CAS No. 362-07-2. Molecular formula: C19H26O3. Mole weight: 302.414. | |
2-Methoxyestradiol Quick inquiry Where to buy Suppliers range | Off-white solid. Group: Steroidal Compounds. Alternative Names: 2-methoxy-17beta-estradiol; 2-METHOXYESTRADIOL; 2-Methoxyestradiol; 2-Methoxy-β-estradiol; 2-Methoxy 17β-Estradiol. Grades: 95%+. CAS No. 362-07-2. Molecular formula: C19H26O3. Mole weight: 302.41. IUPAC Name: (8R,9S,13S,14S,17S)-2-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol. Exact Mass: 302.18800. Density: 1.178g/cm³. SMILES: CC12CCC3C (C1CCC2O)CCC4=CC (=C (C=C34)OC)O. InChIKey: CQOQDQWUFQDJMK-SSTWWWIQSA-N. | |
2-Methoxyestradiol Quick inquiry Where to buy Suppliers range | Apoptotic, antiproliferative and antiangiogenic agent, in vitro and in vivo; acts via an estrogen receptor-independent mechanism. Induces p53-induced apoptosis via two pathways: activation of p38 and NF-κB; and activation of JNK and AP-1 leading to Bcl-2 phosphorylation. Also upregulates death receptor 5 and binds to tubulin, inhibiting its assembly. Group: Biochemicals. Grades: Highly Purified. CAS No. 362-07-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
2-METHOXYESTRADIOL Quick inquiry Where to buy Suppliers range | 2 METHOXYESTRADIOL. CAS No. 362-07-2. | |
2-Methoxyestradiol (2- methoxy- estra- 1, 3, 5(10)- triene- 3, 17beta- diol, 2-Hydroxyestradiol 2-methyl ether, NSC659853, 2-ME2, Panzem) Quick inquiry Where to buy Suppliers range | 2-Methoxyestradiol (2-ME) is major estradiol metabolite that acts as a potent inhibitor of endothelial cell proliferation and angiogenesis. It displays little affinity for classical estrogen receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 362-07-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |