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2-((6-Amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one 2-((6-Amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one. Group: Biochemicals. Alternative Names: IC-87114. Grades: Highly Purified. CAS No. 371242-69-2. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C22H19N7O. US Biological Life Sciences. USBiological 6
Worldwide
IC-87114 IC-87114 is a potent and selective PI3Kδ inhibitor with IC50 of 0.5 μM. Synonyms: IC87114; IC-87114; IC 87114. CAS No. 371242-69-2. Molecular formula: C22H19N7O. Mole weight: 397.442. BOC Sciences 10
IC87114, PI3K Inhibitor (2-[6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone) Cell-permeable. A potent, ATP-competitive and selective inhibitor of PI 3-K isoform p110e (IC?? =60nM). Inhibits p110a and p110b only at higher concentrations (>1uM). IC87114 does not inhibit other PIK-related kinases such as ATM, ATR, DNA-PK, and mTOR even at concentrations up to 100uM. Group: Biochemicals. Grades: Highly Purified. CAS No. 371242-69-2. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
Worldwide

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