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PIK 75 hydrochloride PIK-75 is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM. Synonyms: PIK 75 hydrochloride; PIK75 hydrochloride; PIK-75 hydrochloride. Grades: >98%. CAS No. 372196-77-5. Molecular formula: C16H14BrN5O4S.HCl. Mole weight: 488.74. BOC Sciences 8
PIK-75 hydrochloride PIK-75 hydrochloride is a reversible DNA-PK and p110α -selective inhibitor, which inhibits DNA-PK, p110α and p110γ with IC 50 s of 2, 5.8 and 76 nM, respectively. PIK-75 hydrochloride inhibits p110α >200-fold more potently than p110β (IC 50 =1.3 μM) [1] [2]. PIK-75 hydrochloride induces apoptosis [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 372196-77-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13281. MedChemExpress MCE

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