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Asperosaponin VI ususlly comes from the root of Dipsacus asperoides C. Y. Cheng et T. M. Ai. Except for its antioxidant activity, treatment of U937 cells with akebia saponin D (ASD) induced apoptosis in a dose dependent manner. ASD exerted strong cytotoxicity against human and murine leukemia cells. ASD may exert apoptosis-inducing activity via induction of apoptosis through activation chiefly via the nitric oxide and apoptosis-related p53 and Bax gene expression. Uses: Antioxidant. Synonyms: Akebia saponin D; Hederagenin 3-O-alpha-L-arabinopyranosyl-28-beta-D-glucopyranosyl(1?6)-beta-D-glucopyranoside; Asperosaponin ?; Akebia saponin D(Asperosaponin VI); Dipsacaceae saponin. Grades: >98%. CAS No. 39524-08-8. Molecular formula: C47H76O18. Mole weight: 929.1.
Asperosaponin Vi
Asperosaponin VI, A saponin component from Dipsacus asper, induces osteoblast differentiation through BMP-2/p38 and ERK1/2 pathway. Asperosaponin ? inhibits apoptosis in hypoxia-induced cardiomyocyte by increasing the Bcl-2/Bax ratio and decreasing active caspase-3 expression, as well as enhancing of p-Akt and p-CREB. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: White powder. CAS No. 39524-08-8. Molecular formula: C47H76O18. Mole weight: 929.1. Purity: 0.98. IUPACName: [(3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl] (6aS,9R)-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-10-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate. Canonical SMILES: CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)CO)OC6C(C(C(CO6)O)O)O)C)C)C2C1)C)C(=O)OC7C(C(C(C(O7)COC8C(C(C(C(O8)CO)O)O)O)O)O)O)C. Product ID: ACM39524088. Alfa Chemistry ISO 9001:2015 Certified.
Asperosaponin VI
Asperosaponin VI, A saponin component from Dipsacus asper , induces osteoblast differentiation through BMP?2/p38 and ERK1/2 pathway [1]. Asperosaponin ? inhibits apoptosis in hypoxia-induced cardiomyocyte by increasing the Bcl-2/Bax ratio and decreasing active caspase-3 expression, as well as enhancing of p-Akt and p-CREB [2]. Uses: Scientific research. Group: Natural products. CAS No. 39524-08-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0265.
Asperosaponin VI
Asperosaponin VI. Group: Biochemicals. Alternative Names: Akebia saponin D. Grades: Plant Grade. CAS No. 39524-08-8. Pack Sizes: 20mg. Molecular Formula: C47H76O18, Molecular Weight: 929.096. US Biological Life Sciences.
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