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| Product | Description | |
|---|---|---|
| 3PO | 3PO. Group: Biochemicals. Grades: Purified. CAS No. 13309-08-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| 3PO | 3PO inhibits PFKFB3 (IC50 = 25 μM) and has the potential to inhibit the proliferation of cancer cells. Synonyms: (E)-3PO; (E)-3-(pyridin-3-yl)-1-(pyridin-4-yl)prop-2-en-1-one; 3PO (inhibitor of glucose metabolism); 2-Propen-1-one, 3-(3-pyridinyl)-1-(4-pyridinyl)-, (2E)-; (2E)-3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one; 2-Propen-1-one, 1-(4-pyridyl)-3-(3-pyridyl)-, (E)-. Grades: ≥95%. CAS No. 18550-98-6. Molecular formula: C13H10N2O. Mole weight: 210.23. |  |
| 3PO | 3PO is an inhibitor of PFKFB3. 3PO attenuates the proliferation of several cancer cell lines with IC 50 s of 1.4-24 μmol/L. 3PO suppresses glucose uptake and decreases the intracellular concentration of Fru-2,6-BP, lactate, ATP, NAD + and NADH. 3PO can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 18550-98-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19824. |  |
| 3PO | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| PFKFB3 Inhibitor, 3PO (6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 Inhibitor, 3PO, 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one, (2E)-3-Pyridin-3-yl-1-pyridin-4-ylprop-2-en-1-one) | A cell-permeable dipyridinyl-propenone compound that selectively blocks PFK-2 (6-phosphofructo-2-kinase) activity of PFKFB3 isozyme over PFK-1 (6-phosphofructo-1-kinase) in a mixed-mode manner. Rapidly decreases fructose-2,6-bisphosphate (F-2,6-P2) and 2-deoxyglucose uptake, and lactate secretion; efficiently arrests proliferation of transformed cells (IC50 ~1.4uM in NHBE-ht/LT/ras) and suppresses tumor growth in several xenograft mouse models (70mg/kg, i.p.). The cytostatic and cytotoxic effects of 3PO is shown to be highly sensitive to the intracellular levels of F-6-P (fructose-6-phosphate) and F-2,6-P2. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Benzyltriphenylphosphonium hydroxide | Benzyltriphenylphosphonium hydroxide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Benzyltriphenylphosphonium hydroxide;Ethyl Triphenylphosphonium Hydroxide;Methyl Triphenylphosphonium Hydroxide;N-Propyl triphenylphosphonium hydroxide;Tetramethylphosphonium hydroxide;Tetrapropylphosphonium hydroxide. Product Category: Heterocyclic Organic Compound. CAS No. 2035-71-4. Molecular formula: (C6H5CH2)(C6H5)3POH. Product ID: ACM2035714. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Diammonium hydrogenphosphate | DryPowder; Liquid; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid;ODOURLESS WHITE CRYSTALS OR POWDER. Group: Electrolytes. Alternative Names: SEC-AMMONIUM HYDROGEN PHOSPHATE; SEC AMMONIUM PHOSPHATE; PHOSPHORUS ICP STANDARD; ammoniummonohydrogenorthophosphate; diammonium; diammoniumacidphosphate; diammoniummonohydrogenphosphate; diammoniumorthophosphate. CAS No. 7783-28-0. Product ID: diazanium; hydrogen phosphate. Molecular formula: 132.06g/mol. Mole weight: (NH4)2HPO4; (NH4)3PO4; (NH4)2HPO4; H9N2O4P. [NH4+].[NH4+].OP(=O)([O-])[O-]. InChI=1S/2H3N.H3O4P/c;;1-5(2, 3)4/h2*1H3;(H3, 1, 2, 3, 4). MNNHAPBLZZVQHP-UHFFFAOYSA-N. |  |
| GTPαS | GTPαS can be accomplished by 50-thiophosphorylation of 7-methylguanosine in (MeO)3PO in the presence of 2,6-lutidine,12 followed by addition of tributylammonium pyrophosphate and subsequent hydrolysis of the trimetaphosphate-like intermediate. Synonyms: Guanosine-5'-(α-thio)-triphosphate, Sodium salt; (1 : 1 Mixture of R; and S; isomers). Grades: ≥ 95 % by HPLC. CAS No. 81570-51-6. Molecular formula: C10H16N5O13P3S (free acid). Mole weight: 539.24 (free acid). | |
| PFK-158 | PFK-158, also known as ACT-PFK-158, is an inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFK-2/FBPase) isoform 3 (PFKFB3) and derivative of 3-(3-pyridinyl)-1-[4-pyridinyl]-2-propen-1-one (3PO), with potential antineoplastic activity. Upon administration, PFKFB3 inhibitor PFK-158 binds to and inhibits the activity of PFKFB3, which leads to the inhibition of both the glycolytic pathway in and glucose uptake by cancer cells. This prevents the production of macromolecules and energy that causes the enhanced cellular proliferation in cancer cells as compared to that of normal, healthy cells. Depriving cancer cells of nutrients and energy leads to the inhibition of cancer cell growth. PFKFB3, an enzyme that catalyzes the conversion of fructose-6-phosphate to fructose-2,6-bisphosphate, is highly expressed and active in human cancer cells; it plays a key role in increasing both glycolytic flux in and proliferation of cancer cells. Synonyms: PFK158; PFK 158; PFK158; ACTPFK158. Grades: >98%. CAS No. 1462249-75-7. Molecular formula: C18H11F3N2O. Mole weight: 328.29. | |
| Potassium vinyltrifluoroborate | Potassium vinyltrifluoroborate. Group: Salt. Alternative Names: POTASSIUM VINYLTRIFLUOROBORATE; Vinyltrifluoroboric acid potassium salt; Borate(1-), ethenyltrifluoro-, potassium (1:1), (T-4)-; 3POTASSIUM VINYLTRIFLUOROBORATE; POTASSIUM VINYLTRIFLUOROBORATE, TECHNICAL; Vinylboronic acid trifluoroborate potassium salt; Potassium ethenyltrifluoroborate; potassiuM trifluoro-vinyl-boron. CAS No. 13682-77-4. Product ID: potassium; ethenyl(trifluoro)boranuide. Molecular formula: 133.95g/mol. Mole weight: C2H3BF3K. [B-](C=C)(F)(F)F.[K+]. InChI=1S/C2H3BF3.K/c1-2-3(4, 5)6;/h2H, 1H2;/q-1;+1. ZCUMGICZWDOJEM-UHFFFAOYSA-N. | |
| tri-Ammonium phosphate trihydrate | 1kg Pack Size. Group: Salts. Formula: (NH4)3PO4 ·3(H2O). CAS No. 25447-33-0. Prepack ID 11810524-1kg. Molecular Weight 203.13. See USA prepack pricing. |  |
| Triisopropyl phosphate | analytical standard. Group: Flame retardants standardsflame retardants. Alternative Names: Isopropyl phosphate ((C3H7O)3PO) (6CI,7CI), Triisopropoxyphosphine oxide, Phosphoric acid, triisopropyl ester (8CI), NSC 62275, NSC 46370, Triisopropyl phosphate. | |
| Triphenyl phosphate | 31P-qNMR Standard. Group: Quantitative nmrflame retardantsfood contact materials. Alternative Names: Disflamoll TP, TP, Triphenyl phosphate, Wako TPP, DHPF 005, TTP, S 4 (phosphate), TPP, WSFR-TPP, Reofos TPP, TFF,Phosphoric acid, triphenyl ester, S 4, Celluflex TPP, NSC 57868, Phoscon FR 903N, TTP (triphenyl phosphate), Phenyl phosphate ((PhO)3PO), Phosflex TPP, Triphenoxyphosphine oxide, Triphenol phosphate, TPPA, Sumilizer TPP. | |
| Triphenyl phosphate | quantitative NMR; Flame Retardants; Food Contact Materials. Uses: For analytical and research use. Group: Reagents. Alternative Names: Disflamoll TP, TP, Triphenyl phosphate, Wako TPP, DHPF 005, TTP, S 4 (phosphate), TPP, WSFR-TPP, Reofos TPP, TFF,Phosphoric acid, triphenyl ester, S 4, Celluflex TPP, NSC 57868, Phoscon FR 903N, TTP (triphenyl phosphate), Phenyl phosphate ((PhO)3PO), Phosflex TPP, Triphenoxyphosphine oxide, Triphenol phosphate, TPPA, Sumilizer TPP. CAS No. 115-86-6. Pack Sizes: 1G. IUPAC Name: triphenyl phosphate. | |
| Triphenyl Phosphate | Triphenyl phosphate appears as colorless crystals. (NTP, 1992);Liquid; PelletsLargeCrystals; PelletsLargeCrystals, Liquid;COLOURLESS CRYSTALLINE POWDER WITH CHARACTERISTIC ODOUR.;Colorless, crystalline powder with a phenol-like odor.;Colorless, crystalline powder with a phenol-like odor. Group: Polymers. Product ID: triphenyl phosphate. Molecular formula: 326.3g/mol. Mole weight: (C6H5)3PO4;C18H15O4P;C18H15O4P. C1=CC=C (C=C1)OP (=O) (OC2=CC=CC=C2)OC3=CC=CC=C3. InChI=1S/C18H15O4P/c19-23 (20-16-10-4-1-5-11-16, 21-17-12-6-2-7-13-17) 22-18-14-8-3-9-15-18/h1-15H. XZZNDPSIHUTMOC-UHFFFAOYSA-N. | |
| Triphenyl phosphate-d15 | Triphenyl phosphate-d 15 is the deuterium labeled Triphenyl phosphate[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Celluflex TPP-d15; DHPF 005-d15; Disflamol TP-d15; Disflamoll TP-d15; NSC 57868-d15; Phenyl phosphate ((PhO)3PO)-d15; Phoscon FR 903N-d15. CAS No. 1173020-30-8. Pack Sizes: 2.5 mg. Product ID: HY-Y1322S. | |
| Triphenyl Phosphate, Reagent | Triphenyl phosphate appears as colorless crystals. (NTP, 1992);Liquid; PelletsLargeCrystals; PelletsLargeCrystals, Liquid;COLOURLESS CRYSTALLINE POWDER WITH CHARACTERISTIC ODOUR.;Colorless, crystalline powder with a phenol-like odor.;Colorless, crystalline powder with a phenol-like odor. Group: Plasticizers. CAS No. 115-86-6. Product ID: triphenyl phosphate. Molecular formula: 326.3g/mol. Mole weight: (C6H5)3PO4;C18H15O4P;C18H15O4P. C1=CC=C (C=C1)OP (=O) (OC2=CC=CC=C2)OC3=CC=CC=C3. InChI=1S/C18H15O4P/c19-23 (20-16-10-4-1-5-11-16, 21-17-12-6-2-7-13-17) 22-18-14-8-3-9-15-18/h1-15H. XZZNDPSIHUTMOC-UHFFFAOYSA-N. | |
| Triphenylphosphine oxide | Triphenylphosphine oxide. Uses: Flame retardant. Group: Ligands for functional metal complexes. Alternative Names: Phosphine oxide, triphenyl-; Triphenyl phosphorus oxide; (C6H5)3P=O; Triphenylphosphanoxid; Triphenylphosphanoxide; (C6H5)3PO; Triphenylphosphine oxide; Triphenyl phosphorus oxide. CAS No. 791-28-6. Product ID: diphenylphosphorylbenzene. Molecular formula: 278.28. Mole weight: C18H15OP. C1=CC=C (C=C1)P (=O) (C2=CC=CC=C2)C3=CC=CC=C3. 1S/C18H15OP/c19-20 (16-10-4-1-5-11-16, 17-12-6-2-7-13-17) 18-14-8-3-9-15-18/h1-15H. FIQMHBFVRAXMOP-UHFFFAOYSA-N. 99%. | |
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