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Palovarotene is a selective retinoic acid receptor gamma(RAR-γ) agonist for the treatment of emphysema. In small animal studies, palovarotene was claimed to reverse the structural, functional and inflammatory features of cigarette smoke-induced emphysema. Phase I clinical trials of palovarotene in patients with emphysema demonstrated that the drug is well tolerated, with improvements observed in markers of emphysema progression. Synonyms: 4-[(1E)-2-[5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-3-(1H-pyrazol-1-ylmethyl)-2-naphthalenyl]ethenyl]benzoic Acid; R 667; Ro 3300074; 4-{(E)-2-[5,5,8,8-Tetramethyl-3-(1H-pyrazol-1-ylmethyl)-5,6,7,8-tetrahydro-2-naphthalenyl]vinyl}benzoic acid; (E)-4-(2-(3-((1H-pyrazol-1-yl)methyl)-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic acid. Grades: 98%. CAS No. 410528-02-8. Molecular formula: C27H30N2O2. Mole weight: 414.54.
2-(1H-Pyrazol-1-yl)benzoic acid ≥95% (NMR)
2-(1H-Pyrazol-1-yl)benzoic acid ≥95% (NMR). Group: Biochemicals. Grades: Reagent Grade. CAS No. 55317-53-8. Pack Sizes: 250mg, 1g, 2.5g. US Biological Life Sciences.
Worldwide
3-(1H-pyrazol-1-yl)benzoic acid 99+% (LCMS)
3-(1H-pyrazol-1-yl)benzoic acid 99+% (LCMS). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
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