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| Product | Description | |
|---|---|---|
| 4-DAMP | 4-DAMP (4-DAMP methiodide) is a potent and selective antagonist of M3 receptors and also has a high affinity for the closely-related M5 receptors. 4-DAMP combined with 5-Fluorouracil (5-Fu) (HY-90006) could significantly reduce the cell viability and enhance apoptosis in MKN45 and BGC823 gastric cancer cells. 4-DAMP inhibits lipopolysaccharide (LPS)- and tobacco-induced pulmonary inflammation and reduces mucin 5AC (MUC5AC), oligomeric mucus/gel-forming secretion [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-DAMP methiodide. CAS No. 1952-15-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100958. |  |
| 4-DAMP | 4-DAMP is a potent and selective antagonist of the M3 cholinergic receptor. [3H]-4-DAMP selectively labels M1 and M3 receptors. Blockade of mAChR M2 leads to a decrease of blood pressure in dose manner in spotaneously hypertensive rats. Synonyms: 1,1-Dimethyl-4-diphenylacetoxypiperidinium iodide; 4-Damp methiodide; 4-Diphenylacetoxy-N-methylpiperidine methiodide; 4-DAMP iodide. Grades: ≥99% by HPLC. CAS No. 1952-15-4. Molecular formula: C21H26INO2. Mole weight: 451.33. |  |
| 4-DAMP | 4-DAMP is a potent antagonist of the muscarinic M3 receptor (pKi = 9.3). It is routinely used to study the regulation and functions of the M3 receptor. 4-DAMP also has a high affinity for the closely-related M5 receptor (pKi = 8.9). Group: Biochemicals. Alternative Names: 4-[(2,2-Diphenylacetyl)oxy]-1,1-dimethylpiperidinium Iodide (1:1); 4-[(Diphenylacetyl)oxy]-1,1-dimethyl-Piperidinium Iodide (9CI); 4-Hydroxy-1,1-dimethyl-piperidinium Iodide Diphenylacetate; 4-Benziloyloxy-N-methylpiperidine Methiodide; 4-DAMP; 4-DAMP Methiodide; 4-Diphenylacetoxy-N-methylpiperidine Methiodide; 4-Diphenylacetyloxy-N-methylpiperidine Methiodide; N, N-Dimethyl-4- (diphenylacetoxy) piperidinium Iodide. Grades: Highly Purified. CAS No. 1952-15-4. Pack Sizes: 25mg, 50mg, 100mg. Molecular Formula: C21H26INO2, Molecular Weight: 451.34. US Biological Life Sciences. |  Worldwide |
| 4-DAMP | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| 3,3-Diphenylpropionyl Chloride | An intermediate used for the synthesis of cardioprotectants, 4-DAMP analogs, and other pharmaceutical agents. Group: Biochemicals. Alternative Names: β-Phenyl-. Grades: Highly Purified. CAS No. 37089-77-3. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
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