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| Product | Description | |
|---|---|---|
| 4-Hydroxysphinganine | 4-Hydroxysphinganine. Group: Biochemicals. Alternative Names: D-Phytosphingosine; (2S, 3S, 4R)-2-Amino-1,3,4-octadecanetriol. Grades: Highly Purified. CAS No. 388566-94-7,554-62-1. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C18H39NO3. US Biological Life Sciences. |  Worldwide |
| 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase | The enzyme, characterized from yeast and mammals, catalyses the hydroxylation of carbon 2 of long- or very-long-chain fatty acids attached to (4R)-4-hydroxysphinganine during de novo ceramide synthesis. The enzymes from yeast and from mammals contain an N-terminal cytochrome b5 domain that acts as the direct electron donor to the desaturase active site. The newly introduced 2-hydroxyl group has R-configuration. cf. EC 1.14.18.7, dihydroceramide fatty acyl 2-hydroxylase. Group: Enzymes. Synonyms: FA2H (gene name); SCS7 (gene name). Enzyme Commission Number: EC 1.14.18.6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0968; 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase; EC 1.14.18.6; FA2H (gene name); SCS7 (gene name). Cat No: EXWM-0968. |  |
| N-Octanoyl 4-hydroxysphinganine | N-Octanoyl 4-hydroxysphinganine. Group: Biochemicals. Alternative Names: N-Octanoyl-phytosphingosine. Grades: Highly Purified. CAS No. 475995-74-5. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C26H53NO4. US Biological Life Sciences. | Worldwide |
| dihydroceramide fatty acyl 2-hydroxylase | The enzyme, characterized from plants, catalyses the hydroxylation of carbon 2 of long- or very-long-chain fatty acids attached to sphinganine during de novo ceramide synthesis. The enzyme requires an external cytochrome b5 as the electron donor. The newly introduced 2-hydroxyl group has R-configuration. cf. EC 1.14.18.6, 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase. Group: Enzymes. Synonyms: FAH1 (gene name); FAH2 (gene name); plant sphingolipid fatty acid 2-hydroxylase. Enzyme Commission Number: EC 1.14.18.7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0969; dihydroceramide fatty acyl 2-hydroxylase; EC 1.14.18.7; FAH1 (gene name); FAH2 (gene name); plant sphingolipid fatty acid 2-hydroxylase. Cat No: EXWM-0969. | |
| N-Acetyl-phytosphingosine | N-Acetyl-phytosphingosine. Group: Biochemicals. Alternative Names: N-Acetyl (2S, 3S, 4R)-2-amino-1,3,4 -octadecanetriol; N-Acetyl 4-hydroxysphinganine. Grades: Highly Purified. CAS No. 475995-69-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C20H41NO4. US Biological Life Sciences. | Worldwide |
| Phytosphingosine | Phytosphingosine is a phospholipid with anti-inflammatory, antibacterial, and anti-cancer activities, which can induce apoptosis. Phytosphingosine is an immune regulator and can be used in the study of inflammatory skin diseases. Phytosphingosine is also an activator of GPR120 with an IC 50 value of 33.4 μM and can be used in the study of type II diabetes [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: 4-Hydroxysphinganine. CAS No. 554-62-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W011303. |  |
| sphingolipid 8-(E)-desaturase | The enzyme, characterized from the yeasts Kluyveromyces lactis and Candida albicans and from the diatom Thalassiosira pseudonana, introduces a trans double bond at the 8-position of sphingoid bases in sphingolipids. The enzyme determines the position of the double bond by its distance from the alcohol end of the sphingoid base, and contains a cytochrome b5 domain that acts as the direct electron donor to the active site of the desaturase. The homologous enzymes from higher plants, EC 1.14.19.29, sphingolipid 8-(E/Z)-desaturase, act on phytosphinganine (4-hydroxysphinganine) and produces a mixture of trans and cis isomers. Group: Enzymes. Synonyms: 8-sphingolipid desaturase (ambiguous); 8 fatty acid desaturase (ambiguous); DELTA8-sphingolipid desaturase (ambiguous). Enzyme Commission Number: EC 1.14.19.18. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0980; sphingolipid 8-(E)-desaturase; EC 1.14.19.18; 8-sphingolipid desaturase (ambiguous); 8 fatty acid desaturase (ambiguous); DELTA8-sphingolipid desaturase (ambiguous). Cat No: EXWM-0980. | |
| sphingosine kinase | The enzyme is involved in the production of sphingolipid metabolites. It phosphorylates various sphingoid long-chain bases, such as sphingosine, D-erythro-dihydrosphingosine (sphinganine), phytosphingosine (4-hydroxysphinganine), 4-hydroxy-8-sphingenine, 4,8-sphingadienine and D-threo-dihydrosphingosine and L-threo-dihydrosphingosine. The exact substrate range depends on the species. Group: Enzymes. Synonyms: SPHK1 (gene name); SPHK2 (gene name); dihydrosphingosine kinase; dihydrosphingosine kinase (phosphorylating); sphingosine kinase (phosphorylating); sphingoid base kinase; sphinganine kinase; ATP:sphinganine 1-phosphotransferase. Enzyme Commission Number: EC 2.7.1.91. CAS No. 50864-48-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3121; sphingosine kinase; EC 2.7.1.91; 50864-48-7; SPHK1 (gene name); SPHK2 (gene name); dihydrosphingosine kinase; dihydrosphingosine kinase (phosphorylating); sphingosine kinase (phosphorylating); sphingoid base kinase; sphinganine kinase; ATP:sphinganine 1-phosphotransferase. Cat No: EXWM-3121. | |
| D-ribo Phytosphingosine 1-Phosphate | A potential modulator of cellular processes. A high affinity ligand for the S1P4/Edg-6 receptor. Group: Biochemicals. Alternative Names: (2S,3S,4R)-Hydroxysphinganine 1-Phosphate. Grades: Highly Purified. CAS No. 38597-28-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
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