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2-[(4-methoxyphenyl)methoxy]ethyl 4-methylbenzene-1-sulfonate. Uses: Designed for use in research and industrial production. Product Category: PROTAC Library. CAS No. 354507-05-4. Molecular formula: C17H20O5S. Mole weight: 336.4027. Product ID: PR354507054. Alfa Chemistry ISO 9001:2015 Certified.
2-O-DMT-sulfonyldiethanol phosphoramidite
2-O-DMT-sulfonyldiethanol phosphoramidite substantiates its inevitable prowess in the synthesis and alteration of nucleic acids across diverse applications. Unparalleled in its chemical composition, this exceptional concoction facilitates meticulous and efficient manipulation of nucleic acids, thus fostering elevated biomedical exploration with incomparable precision. Synonyms: 2-((2-(bis(4-methoxyphenyl)(phenyl)methoxy)ethyl)sulfonyl)ethyl (2-cyanoethyl) diisopropylphosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-[[2-[bis(4-methoxyphenyl)phenylmethoxy]ethyl]sulfonyl]ethyl 2-cyanoethyl ester; 2-[2-(4,4'-dimethoxytrityloxy)ethylsulfonyl]ethyl-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; 2-O-DMT-S phosphoramidite; 5'-Phosphate-Amidite; O-DMT-2,2'-sulfonyldiethanol phosphoramidite; 5'-Phosphate-ON Reagent. Grade: >95% by HPLC. CAS No. 108783-02-4. Molecular formula: C34H45N2O7PS. Mole weight: 656.77.
Methyl 1-[(4-methoxyphenyl)sulfonyl]-1H-indole-3-carboxylate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: METHYL 1-[(4-METHOXYPHENYL)SULFONYL]-1H-INDOLE-3-CARBOXYLATE;1H-INDOLE-3-CARBOXYLIC ACID, 1-[(4-METHOXYPHENYL)SULFONYL]-,METHYL ESTER. Product Category: Heterocyclic Organic Compound. CAS No. 866145-32-6. Molecular formula: C17H15NO5S. Mole weight: 345.37. Product ID: ACM866145326. Alfa Chemistry ISO 9001:2015 Certified.
A cell-permeable phenyl sulfonyl oxyimi nocyclohexadienone compound that acts as a potent, selective, and reversible inhibitor of p300 histone acetyl transferase (IC50 = 1.98uM). Shown to occupy Ac-CoA binding pocket of p300, and less potent to CBP, PCAF, GCN5 and GNAT. Suppresses Histone H3 and H4 acetylation in triple negative breast cancer cell line MDAMB-468 as well as in HCT116 cell line and blocks p300-mediated STAT3 phosphorylation in pancreatic cancer cell line MIA Paca-2. Does neither inhibit the activities of histone deacetylases 1, 6, and 11 nor 8-diverse histone methyltransferases tested (DOT1, EZH1, G9a, PRMT1, SETD2, SET7-9, SMYD2, and SUV39H2). Reported to suppress tumor growth in mice bearing tumor xenografts of MDAMB-468 cell line (at 500ug/100ul, i.p. twice a week). Group: Biochemicals. Grades: Highly Purified. CAS No. 321695-57-2. Pack Sizes: 10mg. Molecular Formula: C??H??NO?S. US Biological Life Sciences.
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