4311 88 0 Suppliers USA
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Product | Description | |
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Methylthiohydantoin-DL-tryptophan Quick inquiry Where to buy Suppliers range | Methylthiohydantoin DL tryptophan. CAS No. 4311-88-0. | |
Necrostatin-1 Quick inquiry Where to buy Suppliers range | Competitive indoleamine 2,3-dioxygenase (IDO) inhibitor. Cell permeable, potent and selective necroptosis (a non-apoptotic form of programmed cell death) inhibitor. Showed neuroprotection in a murine model of ischemic brain injury in vivo. Selective and ATP-competitive receptor-interacting protein kinase 1 (RIPK1) inhibitor. Used in inflammatory and degenerative disease models to target RIPK1. Suppresses autophagy and apoptosis in murine brain injury models. Group: Biochemicals. Alternative Names: Nec-1, MTH-Trp, MTH-DL-Tryptophan, Methyl-thiohydantoin DL-tryptophan, 5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone. Grades: Highly Purified. CAS No. 4311-88-0. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??N?OS. US Biological Life Sciences. | Worldwide |
Necrostatin-1 Quick inquiry Where to buy Suppliers range | Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM. Synonyms: Necrostatin-1; Necrostatin1; Necrostatin 1; Nec-1; Nec 1; Nec1. Grades: >98%. CAS No. 4311-88-0. Molecular formula: C13H13N3OS. Mole weight: 259.33. | |
Necrostatin-1 (5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone, Methylthiohydantoin-DL-tryptophan, Nec-1) Quick inquiry Where to buy Suppliers range | Inhibits necroptosis, a non-apoptotic cell death pathway. Does not inhibit FAS-induced apoptosis and has no effect on apoptotic morphology. Inhibits RIP1 kinase, the key upstream kinase involved in the activation of necroptosis (EC50 = 180nM). Group: Biochemicals. Alternative Names: 5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone; 5-(Indol-3-ylmethyl)-3-methyl-2-thiohydantoin; Nec 1. Grades: Highly Purified. CAS No. 4311-88-0. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |