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SMI-4a SMI-4a (TCS-PIM-1-4a) is a poten, selective, cell-permeable and ATP-competitive Pim-1 inhibitor with an IC50 of 24 ?M and a Ki of 0.6 ?M. SMI-4a also inhibits Pim-2 (IC50 of 100 ?M), and does not significantly inhibit the other serine/threonine- or tyrosine-kinases. SMI-4a has anticancer activity[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TCS-PIM-1-4a. CAS No. 438190-29-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16576A. MedChemExpress MCE
TCS PIM-1 4a TCS PIM-1 4a. Group: Biochemicals. Grades: Purified. CAS No. 438190-29-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
(Z)-SMI-4a (Z)-SMI-4a is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM for Pim-1 compared to an IC50 of 100 nM for Pim-2 and with little or no activity against a panel of 50 other kinases tested. Synonyms: SMI-4a; SMI4a; SMI 4a; TCS PIM-1 4a. CAS No. 438190-29-5. Molecular formula: C11H6F3NO2S. Mole weight: 273.229. BOC Sciences 9

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