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Product | Description | |
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2-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine Quick inquiry Where to buy Suppliers range | 2-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine. Group: Main Products. Alternative Names: ALK5 INHIBITOR I;2-(3-(6-METHYLPYRIDIN-2-YL)-1H-PYRAZOL-4-YL)-1,5-NAPHTHYRIDINE;TGF-BETA RI KINASE INHIBITOR II;TRANSFORMING GROWTH FACTOR-BETA TYPE I RECEPTOR KINASE INHIBITOR I;2-(3-(6-Methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine;SJN 2511;2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine;RepSox. Grades: 98%+. CAS No. 446859-33-2. Product ID: ACM446859332. Molecular formula: C17H13N5. Mole weight: 287.31862. IUPAC Name: 2-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine. Boiling Point: 501.911ºC at 760 mmHg. Flash Point: 230.461ºC. Density: 1.297g/cm³. | |
Alk 5 Inhibitor II Quick inquiry Where to buy Suppliers range | Alk 5 Inhibitor II. Group: Biochemicals. Alternative Names: 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine; E 616452; RepSox; SJN 2511. Grades: Highly Purified. CAS No. 446859-33-2. Pack Sizes: 10mg. Molecular Formula: C17H13N5, Molecular Weight: 287.32. US Biological Life Sciences. | Worldwide |
ALK5 Inhibitor II hydrochloride Quick inquiry Where to buy Suppliers range | ALK5 inhibitor II was identified as a cell permeable, selective inhibitor of the TGF-β type 1 activin like kinase receptor ALK5 (ALK5 autophosphorylation, IC50s = 4 nM, TGF-β cellular assay, IC50s = 18 nM, ALK5 binding in HepG2 cells, IC50s = 23 nM). This compound has been used to induce stem cell pluripotency by replacing the reprogramming transcription factor Sox2 via inhibition of the TGF-β signaling pathway and induction of Nanog transcription. This product is a hydrochloride form. Synonyms: E 616452; RepSox; SJN 2511. Grades: ≥98%. CAS No. 446859-33-2. Molecular formula: C17H13N5·HCl. Mole weight: 323.8. | |
RepSox Quick inquiry Where to buy Suppliers range | RepSox. Group: Biochemicals. Grades: Purified. CAS No. 446859-33-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
RepSox (2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine, E-616452) Quick inquiry Where to buy Suppliers range | Cell-permeable. A TGF-b type I receptor (ALK5) inhibitor. Inhibits ALK5 autophosphorylation (IC??=4nM). Can replace one of the four reprogramming factors Sox-2. RepSox has been successfully used in the direct reprogramming of mouse fibroblasts through induction of Nanog transcription. Group: Biochemicals. Grades: Highly Purified. CAS No. 446859-33-2. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |