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5'-Amino-5'-deoxythymidine. Group: Biochemicals. Grades: Highly Purified. CAS No. 25152-20-9. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C10H15N3O4. US Biological Life Sciences.
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5'-Amino-5'-deoxythymidine
It is used in the methods and compositions for treatment of anti-angiogenic resistant cancer. Synonyms: NSC 169339; 1-((2R,4S,5R)-5-(Aminomethyl)-4-hydroxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 5-Addot; 5'-Amino-2',5'-dideoxythymidine; 5'-deoxy-5'-aminothymidine. Grades: ≥95%. CAS No. 25152-20-9. Molecular formula: C10H15N3O4. Mole weight: 241.24.
3'-Amino-3'-deoxythymidine
A metabolite of Zidovudine (3'-Azido-3'-deoxythymidine; AZT). Uses: A metabolite of zidovudine (3'-azido-3'-deoxythymidine; azt). Synonyms: 3'-Amino-3'-deoxy-thymidine; 3'-Deoxy-3'-aminothymidine; AMT; 1-((2R,4S,5S)-4-Amino-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione. Grades: 98%. CAS No. 52450-18-7. Molecular formula: C10H15N3O4. Mole weight: 241.24.
5'-Amino-5'-deoxy-5'-N-MMT-thymidine 3'-CE phosphoramidite, a compound of utmost importance in the biomedical sector, serves as a pivotal entity for crafting modified oligonucleotides. Leveraging its inherent amino and thymidine elements, this phosphoramidite contributes significantly to the advancement of nucleic acid-centered therapeutics, diagnostics, and gene expression investigations. Synonyms: 5'-monomethoxytritylamino-2'-deoxyThymidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5'-Amino-dT-CE Phosphoramidite. CAS No. 194034-71-4. Molecular formula: C39H48N5O6P. Mole weight: 713.81.
Pemetrexed Alpha-Hydroxy Lactum Isomer II
Pemetrexed alpha-hydroxy lactum isomer II is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: (2R)-2-(4-(2-(2-Amino-5-hydroxy-4,6-dioxo-4,5,6,7-tetrahydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic Acid. Molecular formula: C20H21N5O8. Mole weight: 459.41.
3'-O-Aminothymidine
3'-O-Aminothymidine, a nucleoside analogue, is efficacious in treating different viral infections such as HIV and hepatitis B by restricting viral DNA synthesis and hindering further viral multiplication. Remarkably, it exhibits promising therapeutic effects against certain cancer types, notably leukemia and lymphoma. Its antiviral and antiproliferative properties make it an excellent candidate for drug development and treatment. Synonyms: 3'-O-Amino-dT; 3'-O-Amino-2'-deoxythymidine; 1-(3-O-Amino-2-deoxypentofuranosyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one; 1-((2R,4S,5R)-4-(Aminooxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione. Grades: ≥98% by HPLC. CAS No. 103251-38-3. Molecular formula: C10H15N3O5. Mole weight: 257.24.
Pemetrexed Tromethamine Amide
Pemetrexed tromethamine amide is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: (S)-tert-Butyl 2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-((1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)amino)-5-oxopentanoate. Molecular formula: C28H38N6O8. Mole weight: 586.64.
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