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| Product | Description | |
|---|---|---|
| 5-(N,N-Hexamethylene)-amiloride | 5-(N,N-Hexamethylene)-amiloride derives from an amiloride and is a potent Na+/H+ exchanger inhibitor, which decreases the intracellular pH (pHi) and induces apoptosis in leukemic cells. It is also an inhibitor of the HIV-1 Vpu virus ion channel and inhibits mouse hepatitis virus (MHV) replication and human coronavirus 229E (HCoV229E) replication in cultured L929 cells with EC50s of 3.91 μM and 1.34 μM, respectively. Synonyms: Hexamethylene amiloride; HMA. Grades: 0.98. CAS No. 1428-95-1. Molecular formula: C12H18ClN7O. Mole weight: 311.77. |  |
| 5-(N,N-Hexamethylene)-amiloride | 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) derives from an amiloride and is a potent Na + /H + exchanger inhibitor, which decreases the intracellular pH (pH i ) and induces apoptosis in leukemic cells. 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) is also an inhibitor of the HIV-1 Vpu virus ion channel and inhibits mouse hepatitis virus (MHV) replication and human coronavirus 229E (HCoV229E) replication in cultured L929 cells with EC 50 s of 3.91 μM and 1.34 μM, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Hexamethylene amiloride; HMA. CAS No. 1428-95-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-128067. |  |
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