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1g Pack Size. Group: Biochemicals, Building Blocks. Formula: C9H11FN2O5. CAS No. 50-91-9. Prepack ID 27134875-1g. Molecular Weight 246.19. See USA prepack pricing.
5-Fluoro-2'-deoxyuridine 5'-Monophosphate Ammonium Salt (up to 20% 3'-monophosphate)
5-Fluoro-2'-deoxyuridine 5'-Monophosphate is used in the preparation of diaminomitosene nucleotide derivatives with anti-neoplastic activity. Synonyms: 2'-Deoxy-5-fluoro-5'-uridylic Acid Ammonium Salt. Grades: 90%. Molecular formula: C9H12FN2O8P xNH3. Mole weight: 326.17.
5-Fluoro-2'-deoxyuridine-5'-triphosphate (triethylammonium salt form)
An impurity of UTP. UTP is a pyrimidine nucleoside triphosphate as a substrate in the biosynthesis of RNA. Synonyms: FdUTP (triethylammonium salt form). Grades: 95%. CAS No. 1621676-99-0. Molecular formula: C9H14N2O14P3F.C6H15N. Mole weight: 486.135 (free acid).
5-Fluoro-2'-deoxyuridine, 99+%
5-Fluoro-2'-deoxyuridine, 99+%. Group: Biochemicals. Alternative Names: 5-Fluoro-2'-deoxy-D-uridine; Floxuridine; 2'-Deoxy-5-fluorouridine; 1-(2-Deoxy--D-ribofuranosyl)-5-fluorouracil; NSC-27640; FUDR. Grades: Reagent Grade. CAS No. 50-91-9. Pack Sizes: 250mg, 1g, 5g, 25g. Molecular Formula: C9H11FN2O5, Molecular Weight: 246.19. US Biological Life Sciences.
Worldwide
3',5'-Di-O-acetyl-5-fluoro-2'-deoxyuridine
3',5'-Di-O-acetyl-5-fluoro-2'-deoxyuridine is a derivative of 2'-Fluoro-2'-deoxyuridine, which is a component incorporated into therapeutic oligonucleotides to combat prostate and breast cancer. Synonyms: 1-(3,5-Di-O-acetyl-2-deoxy-α-D-erythro-pentofuranosyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione. CAS No. 110522-47-9. Molecular formula: C13H15FN2O7. Mole weight: 330.27.
3'-O-TBDMS-5-Fluoro-2'-deoxyuridine
3'-O-TBDMS-5-Fluoro-2'-deoxyuridine, a nucleoside analog, exhibits great potential for cancer research and treatment. Known to impede DNA synthesis and trigger apoptosis in cancerous cells, this promising compound proves effective in tackling various malignancies, such as those found in the breast, lung, and pancreas. While it holds great scientific significance in cancer biology, its diagnostic capabilities in tracking cancer development further increase its value as a tool for medical professionals. Synonyms: 3'-O-TBDMS-5-F-dU; 1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidine-2,4-dione; 3'-O-t-Butyldimethylsilyl-5-fluoro-2'-deoxyuridine; 3'-O-(tert-Butyldimethylsilyl)-5-fluoro-2'-deoxyuridine; 2'-Deoxy-3'-O-[dimethyl(2-methyl-2-propanyl)silyl]-5-fluorouridine; Uridine, 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-5-fluoro-. Grades: ≥97% by HPLC. Molecular formula: C15H25FN2O5Si. Mole weight: 360.46.
5-Fluoro-2-deoxyuridine 5-Monophosphate Disodium Salt
5-Fluoro-2-deoxyuridine 5-Monophosphate is used in the preparation of diaminomitosene nucleotide derivatives with anti-neoplastic activity. Group: Biochemicals. Alternative Names: 2'-Deoxy-5-fluoro-5'-uridylic Acid Dsodium Salt. Grades: Highly Purified. CAS No. 103226-10-4. Pack Sizes: 10mg. US Biological Life Sciences.
5'-O-DMT-5-Fluoro-2'-deoxyuridine-3'-CE Phosphoramidite is a highly potent reagent for the synthesis of 5-fluorouracil (5-FU) containing oligonucleotides, with potential applications in the treatment of cancer. By boosting the selectivity and efficacy of 5-FU, a well-established chemotherapy drug for different forms of cancer, this compound constitutes a promising avenue to enhance the therapeutic options available to patients. Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-fluoro-, 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-fluoro-uridine 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; FdU-amidite; NSC-729744. Grades: ≥98% by HPLC. CAS No. 142246-63-7. Molecular formula: C39H46FN4O8P. Mole weight: 748.78.
5'-O-TBDMS-5-Fluoro-2'-deoxyuridine
5'-O-TBDMS-5-Fluoro-2'-deoxyuridine, a nucleoside analogue employed as antiviral therapy for herpes simplex virus, varicella zoster virus, and cytomegalovirus infections in immunocompromised subjects, functions by halting elongation of DNA chains via cellular DNA synthesis to impede viral DNA replication. Its effectiveness in this role, derived through rigorous scientific study, makes it a key player in the fight against viral infections. Synonyms: 5'-O-TBDMS-5-F-dU; 5'-O-(tert-Butyldimethylsilyl)-5-fluoro-2'-deoxyuridine; Uridine, 2'-deoxy-5'-O-[(1,1-dimethylethyl)dimethylsilyl]-5-fluoro-; 5'-O-(tert-Butyldimethylsilyl)-2'-deoxy-5-fluorouridine. Grades: ≥97% by HPLC. CAS No. 129816-30-4. Molecular formula: C15H25FN2O5Si. Mole weight: 360.46.
2-Bromobenzyl Alcohol
2-Bromobenzyl Alcohol acts as a reagent for the synthesis of alkoxy tetrasubstituted chiral amino acids via three-component reaction of (diazo)oxindoles, alcohols and benzhydrylimino ester involving enantioselective trapping of oxonium ylides by benzhydrylimino ester. Also acts as a reagent for the preparation of orally active and liver-targeted prodrug of 5-fluoro-2'-deoxyuridine for treatment of hepatocellular carcinoma. Group: Biochemicals. Grades: Highly Purified. CAS No. 18982-54-2. Pack Sizes: 5g, 25g. Molecular Formula: C7H7BrO. US Biological Life Sciences.
Worldwide
2'-Deoxy-5-fluorouridine 5'-monophosphate sodium salt
2'-Deoxy-5-fluorouridine 5'-monophosphate sodium salt, a remarkable compound extensively employed in the biomedical domain due to its exceptional antiviral attributes, brings forth intricacy and diversity. It showcases remarkable effectiveness in combatting various viral infections, chiefly instigated by RNA viruses. This compound profoundly suppresses the replication of distinct viruses, exhibiting immense promise in alleviating ailments like hepatitis C, Zika virus, and respiratory syncytial virus. Synonyms: 5F-dUMP; 5-Fluoro-2'-deoxyuridine 5'-monophosphate sodium salt. Grades: ≥ 85% (HPLC). CAS No. 103226-10-4. Molecular formula: C9H10FN2Na2O8P. Mole weight: 370.14.
2'-Deoxy-5-Fluorouridine 5'-phosphate diammonium salt
2'-Deoxy-5-Fluorouridine 5'-phosphate diammonium salt is an exceptionally potent antiviral compound, widely applied in the study of viral infections such as hepatitis B and C. Functioning in a highly selective manner, it effectively impedes the synthesis of viral DNA and RNA, consequently thwarting viral replication. Synonyms: [(2R,3S,5R)-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate diammonium salt; 5-fluoro-2'-deoxyuridine 5'-monophosphate diammonium salt; Uridine, 2'-deoxy-2'-fluoro-, 5'-(dihydrogen phosphate), diammonium salt; 5'-Uridylic acid, 2'-deoxy-2'-fluoro-, diammonium salt. Grades: ≥95%. CAS No. 99966-08-2. Molecular formula: C9H18FN4O8P. Mole weight: 360.23.
2'-Deoxy-5'-O-DMT-5-fluorouridine
2'-Deoxy-5'-O-DMT-5-fluorouridine, a cutting-edge biomedicine marvel, emerges as a paramount solution for an extensive array of cancerous afflictions. Its unwavering potency arises from its compelling efficacy in thwarting the formidable RNA and DNA synthesis within malignant cells. An unparalleled therapeutic breakthrough, this compound holds immense promise to revolutionize chemotherapy protocols in combating pernicious diseases like breast, colon, and lung cancer. Synonyms: 2'-Deoxy-5'-O-DMT-5-fluoro-D-uridine; 5'-O-DMT-5-fluoro-2'-deoxyuridine. Molecular formula: C30H29FN2O7. Mole weight: 548.57.
3',5'-Di-O-acetyl-5-fluoro-O4-(2,4,6-trimethylphenyl)-2'-deoxyuridine is a highly efficacious antiviral compound, finding extensive application within the biomedical domain for research of viral infections associated with herpes simplex virus (HSV) and varicella-zoster virus (VZV). Its synthetic nature, reminiscent of nucleoside analogues, effectively curtails viral DNA replication via active integration into the nascent DNA strand. This consequential molecular interplay culminates in the termination of the DNA chain, concurrently stifling viral progression. Synonyms: ((2R,3S,5R)-3-acetoxy-5-(5-fluoro-4-(mesityloxy)-2-oxopyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl acetate; [(2R,3S,5R)-3-Acetyloxy-5-[5-fluoro-2-oxo-4-(2,4,6-trimethylphenoxy)pyrimidin-1-yl]oxolan-2-yl]methyl acetate. Grades: 95%. CAS No. 141120-62-9. Molecular formula: C22H25FN2O7. Mole weight: 448.45.
5-Fluoro-dUMP
5-Fluoro-dUMP is a reagent used in the synthesis of diaminomitosene nucleotide derivatives with antineoplastic activity. Synonyms: (5F-dUMP); 5-Fluoro-2'-deoxyuridine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 88410-68-8. Molecular formula: C9H12N2O8PF (free acid). Mole weight: 326.17 (free acid).
5-Fluoro-dUTP
5-Fluoro-dUTP is used as the substitute for DNA synthesis catalyzed by DNA polymerases a or Ãfrom calf thymus. 5-Fluoro-dUTP is incorporated into DNA and the incorporated pyrimidine analogs supported further elongation of DNA. Synonyms: 5-F-dUTP; 5-Fl-dUTP; 5-Fluoro-2'-deoxyuridine-5'-Triphosphate. Grades: ≥ 95% by HPLC. Molecular formula: C9H14N2O14P3F (free acid). Mole weight: 486.13 (free acid).
FdUTP
FdUTP, a remarkable nucleoside triphosphate, puts the brakes on thymidylate synthase, striking a fatal blow to DNA precursor synthesis and culminating in cellular collapse. This versatile substance has proven tadpole in tackling a gamut of solid tumors, from the grisly colorectal specter to the dauntingly defiant breast cancer. Synonyms: 5-Fluoro-2'-deoxyuridine-5'-triphosphate. Grades: ≥ 95 % (HPLC). Molecular formula: C9H14N2O14P3F (free acid). Mole weight: 486.1 (free acid).
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