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| Product | Description | |
|---|---|---|
| 5-Hydroxymethyl uridine | 5-Hydroxymethyl uridine is an esteemed compound, having applications in research of varied neurological ailments encompassing Alzheimer's disease and Parkinson's disease. Synonyms: 5-Hydroxymethyluridine; 5-(hydroxymethyl)uridine; Uridine, 5-(hydroxymethyl)-; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(hydroxymethyl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 30414-00-7. Molecular formula: C10H14N2O7. Mole weight: 274.23. |  |
| 5-Hydroxymethyl uridine | 5-Hydroxymethyl uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 30414-00-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W394106. |  |
| 2',3'-Di-O-isopropylidene-5-hydroxymethyluridine | 2',3'-Di-O-isopropylidene-5-hydroxymethyluridine, a nucleoside analogue, has been widely utilized in biomedical research as a vital and consequential substrate for RNA polymerase. The paramountcy of this analog has been accentuated by its incumbent placement in oligonucleotides wherein its impact on RNA structure and function has been meticulously studied. The prospects of this compound have been extolled as it has been observed to proffer inhibitory effects on select viral strains, thereby enhancing its application in the treatment of viral diseases. Synonyms: 5-(hydroxymethyl)-1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidine-2,4(1H,3H)-dione; 2'-O,3'-O-Isopropylidene-5-(hydroxymethyl)uridine; 2',3'-O-Isopropylidene-5-hydroxymethyluridine; 5-Hydroxymethyl-2',3'-(di-O-isopropylidene)uridine; 5-(Hydroxymethyl)-2',3'-O-(1-methylethylidene)uridine; 5-(Hydroxymethyl)-2',3'-O-isopropylideneuridine. Grades: ≥95%. CAS No. 3816-77-1. Molecular formula: C13H18N2O7. Mole weight: 314.29. | |
| 5-Hydroxymethyl-2',3'-di-O-isopropylidene-2-thiouridine | 5-Hydroxymethyl-2',3'-di-O-isopropylidene-2-thiouridine is a profoundly effective compound, meticulously utilized for research of pernicious viral infections triggered by RNA viruses. Its exceptional antiviral characteristics stem from its remarkable affinity towards targeting specific viral enzymes, unfolding a paradigm shift towards obstructing viral replication and mitigating virus-induced pathogenesis. Synonyms: 5-(hydroxymethyl)-1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; 2'-O,3'-O-Isopropylidene-5-(hydroxymethyl)-2-thiouridine; 5-(hydroxymethyl)-2',3'-O-(1-methylethylidene)-2-thio-uridine; 5-(Hydroxymethyl)-1-(2,3-O-isopropylidene-β-D-ribofuranosyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone. Grades: ≥95%. CAS No. 58479-71-3. Molecular formula: C13H18N2O6S. Mole weight: 330.36. | |
| 5-Hydroxymethyl-2'-O-(2-methoxyethyl)uridine | 5-Hydroxymethyl-2'-O-(2-methoxyethyl)uridine is an acclaimed compound, quashing viral replication and precipitously diminishing the burden of viral entities. Synonyms: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-5-(hydroxymethyl)pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 2095417-51-7. Molecular formula: C13H20N2O8. Mole weight: 332.31. | |
| 5-Hydroxymethylxylo-uridine | 5-Hydroxymethylxylo-uridine is a potent biomedical compound widely utilized in the realm of neurology, exhibiting remarkable neuroprotective efficacy. Synonyms: 5-hydroxymethyl-1-β-D-xylofuranosyl-1H-pyrimidine-2,4-dione; 1-β-D-Xylofuranosyl-5-hydroxymethyl-uracil; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-hydroxymethyl-1H-pyrimidine-2,4-dione; 1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(hydroxymethyl)pyrimidine-2,4-dione; 5-(Hydroxymethyl)-1-(β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 52448-09-6. Molecular formula: C10H14N2O7. Mole weight: 274.23. | |
| 1-(b-D-Arabinofuranosyl)-5-hydroxymethyluracil | 1-(b-D-Arabinofuranosyl)-5-hydroxymethyluracil, commonly referred to as Vidarabine, is a pivotal compound within the biomedical sector. Renowned for its antiviral properties, this medication plays a vital role in combating viral infections induced by herpes simplex and varicella-zoster viruses. By hindering viral DNA synthesis, 1-(b-D-Arabinofuranosyl)-5-hydroxymethyluracil effectively curtails viral replication and propagation. Synonyms: 5-Hydroxymethyl-arabino-uridine; 1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(hydroxymethyl)pyrimidine-2,4(1H,3H)-dione; 5-Hydroxymethyl-arauridine; 1-(β-D-Arabinofuranosyl)-5-(hydroxymethyl)-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 28608-82-4. Molecular formula: C10H14N2O7. Mole weight: 274.23. | |
| 5-hme-UTP | 5-hme-UTP, the cutting-edge solution widely applied in biomedicine to scrutinize RNA, is a remarkable discovery. This chemically modified uridine triphosphate profoundly enriches RNA, rendering it selectively detectable. Expeditions using 5-hme-UTP have evinced its dendritic distribution, unveiling molecular sequences implicated in sundry ailments like cancer and neurodegenerative diseases. Hence, 5-hme-UTP has emerged as a pivotal tool to dissect RNA patterns and unravel the indelible complexities of life. Synonyms: 5-Hydroxymethyluridine-5'-Triphosphate; 5-hm-UTP; 5-Hydroxymethyl-UTP; 5-HmUTP. Grades: ≥95% by AX-HPLC. Molecular formula: C10H17N2O16P3. Mole weight: 514.7. | |
| 5-(Hydroxymethyl)-2'-deoxyuridine | 5-(Hydroxymethyl)-2'-deoxyuridine is a nucleoside analog with anticancer and antiviral activities. It inhibits the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s = 8.5 and 4 μM, respectively) and multiple human leukemia cell lines (IC50s = 1.7-5.8 μM). 5-(Hydroxymethyl)-2'-deoxyuridine acts synergistically with 5-fluorouracil (5-FU) against HT-29, HCT116, PANC-1, and EKVX cancer cells with no effect on WI38 embryonic lung fibroblasts. Uses: Antineoplastic agents. Synonyms: a-hydroxythymidine; 5-Hydroxymethyl-2'-deoxyuridine; alpha-Hydroxythymidine; 5-Hydroxymethyldeoxyuridine; HMdU; 5-HMdU; 2'-Deoxy-5-(hydroxymethyl)uridine; 1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-5-(2-hydroxymethyl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 5116-24-5. Molecular formula: C10H14N2O6. Mole weight: 258.23. | |
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