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5-O-(tert-butyldimethylsilyl)-5-iodo-2-deoxyuridine is a remarkable and influential substance within the realm of biomedicine. This highly potent antiviral compound possesses immense potential for combating an array of viral infections induced by DNA viruses, most notably the herpes simplex virus (HSV). Earnestly designed to impede viral DNA synthesis, it ingeniously integrates itself into the viral DNA structure, ultimately culminating in chain termination. It is through such a distinctive mode of action that this compound exhibits tremendous prospects for furthering the advancement of antiviral therapeutic approaches. Synonyms: 5'-O-t-Butyldimethylsilyl 2'-deoxy-5-iodouridine; 1-((2R,4S,5R)-5-(((tert-butyldimethylsilyl)oxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione; 2'-Deoxy-5'-O-TBDMS-5-Iodo-Uridine; 5'-O-TBDMS-5-iodo-2'-deoxyuridine; 2'-Deoxy-5'-O-[(1,1-dimethylethyl)dimethylsilyl]-5-iodouridine; 2'-Deoxy-5'-O-[dimethyl(2-methyl-2-propanyl)silyl]-5-iodouridine. Grades: ≥95%. CAS No. 134218-81-8. Molecular formula: C15H25IN2O5Si. Mole weight: 468.36.
2'-Deoxy-5-iodouridine
2'-Deoxy-5-iodouridine. Group: Biochemicals. Alternative Names: 1-(2-Deoxy-b-D-ribofuranosyl)-5-iodouracil; Idoxuridine; Dendrid; 2'-Deoxy-5-iodo-D-uridine; 5-Iodo-2'-deoxyuridine. Grades: Highly Purified. CAS No. 54-42-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C9H11IN2O5. US Biological Life Sciences.
Worldwide
2'-Deoxy-5'-O-DMT-5-iodouridine
2'-Deoxy-5'-O-DMT-5-iodouridine is a formidable nucleoside analog extensively utilized in the realm of biomedical research, principally devised to the research of pernicious viral afflictions. Its noteworthy efficacy in impeding the functioning of distinct viral enzymes portends a propitious means to investigate viral replication and discern plausible targets for therapeutic intervention. Synonyms: 5'-O-DMTr-5-iodo-2'-deoxyuridine; 2'-Deoxy-5'-O-DMT-5-iodo-D-uridine; 1- ( (2R, 4S, 5R)-5- ( (Bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-iodopyrimidine-2, 4 (1H, 3H)-dione; 2'-Deoxy-5-iodo-5'-O-(4,4'-dimethoxytrityl)uridine; 5'-O-(4,4'-Dimethoxytrityl)-5-iodo-2'-deoxyuridine; 5-Iodo-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-5-iodouridine. Grades: ≥95%. CAS No. 104375-88-4. Molecular formula: C30H29IN2O7. Mole weight: 656.46.
2'-Deoxy-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite is a crucial component in the biomedicine industry. It is employed for the synthesis of modified oligonucleotides with potent therapeutic potential. By incorporating this phosphoramidite, the resulting oligonucleotides display enhanced drug efficacy against specific diseases, such as cancer, viral infections, or genetic disorders. This product serves as a valuable tool for researchers and pharmaceutical companies striving to develop innovative nucleotide-based therapies. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-5-iodo-2'-deoxyuridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphorramidite; 5-Iodo-dU-3'-phosphoramidite; 5'-O-DMTr-5-iodo-2'-dU-3'-CED phosphoramidite; 5-I-dU-CE Phosphoramidite; 5'-O-[Bis (4-methoxyphenyl) (phenyl)methyl]-3'-O-[ (2-cyanoethoxy) (diisopropylamino)phosphino]-2'-deoxy-5-iodouridine; 5-Iodo-dU CEP. Grades: 97%. CAS No. 178925-48-9. Molecular formula: C39H46IN4O8P. Mole weight: 856.69.
3',5'-Di-O-acetyl-2'-deoxy-2'-fluoro-5-iodouridine is a remarkably efficacious antiviral compound extensively employed in the biomedical sector. This exceptional compound manifests exceptional inhibiting efficacy against RNA viruse. Its mechanism of action entails impeding viral replication by disrupting the research and development of viral RNA. Synonyms: 5-iodo-3',5'-diacetyl-2'-fluoro-2'-deoxyuridine; 3'',5''-diacetyl-5-iodo-2''-fluoro-2''-deoxyuridine; ((2R,3R,4R,5R)-3-acetoxy-4-fluoro-5-(5-iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl acetate; 2'-Fluoro-3'-O,5'-O-diacetyl-5-iodo-2'-deoxyuridine. Grades: ≥95%. CAS No. 565226-18-8. Molecular formula: C13H14FIN2O7. Mole weight: 456.16.
3',5'-Di-O-acetyl-2'-deoxy-5-iodouridine
3',5'-Di-O-acetyl-2'-deoxy-5-iodouridine is an indispensable ingredient in antiviral agents, proven to show efficacy in combating an array of viral infections. By selectively hampering viral RNA synthesis, it can successfully thwart viral replication. This extraordinary compound has exhibited tremendous potential in tackling challenging viral ailments such as herpes simplex virus and cytomegalovirus. Synonyms: 3',5'-Di-O-acetyl-2'-deoxy-5-iodo-D-uridine; 3',5'-Di-O-acetyl-5-iodo-2'-deoxyuridine; 5-iodo-3',5'-di-O-acetyl-2'-deoxyuridine; 5-iodo-2'-deoxyuridine 3',5'-diacetate; 3',5'-Di-O-Ac-5-I-2'-dU. CAS No. 1956-30-5. Molecular formula: C13H15IN2O7. Mole weight: 438.17.
5-Iodo-dUMP
5-Iodo-dUMP is a critical compound extensively utilized in the biomedical field with pivotal function in obstructing DNA enhancement. It can impede the proliferation of malignant cells and thwarting the metastatic cascade. Synonyms: (5I-dUMP); 5-Iodo-2'-deoxyuridine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1763-02-6. Molecular formula: C9H12N2O8PI (free acid). Mole weight: 434.08 (free acid).
5-Iodo-dUTP
5-Iodo-dUTP is used in the synthesis of Texas Red-5-dUTP, a fluorescence-labelled nucleotide analog. Texas Red-5-dUTP is used diagnostically for detection of rearranged SS18 in formalin-fixed, paraffin-embedded synovial sarcoma. Synonyms: 5-Iodo-2'-deoxyuridine-5'-Triphosphate. Grades: ≥ 95% by HPLC. CAS No. 3731-55-3. Molecular formula: C9H14N2O14P3I (free acid). Mole weight: 594.04 (free acid).
Idoxuridine
5-Iodo-2'-deoxyuridine is a nucleoside analog that can be incorporated into viral DNA replication to treat herpes simplex keratitis. Uses: 5-iodo-2'-deoxyuridine is a nucleoside analog treat herpes simplex keratitis. Synonyms: 5-Iodo-2'-deoxyuridine; IDU; 2'-Deoxy-5-iodouridine; 5-Iodo-2'-deoxy-D-uridine; 1-(2-Deoxy-β-D-ribofuranosyl)-5-iodouracil; IUdR; Dendrid; Emanil; NSC 39661; Ophthalmadine; Herpesil; Herpidu; Herplex; Stoxil; Stoxip; Synmiol; Virudox. Grades: ≥98% by HPLC. CAS No. 54-42-2. Molecular formula: C9H11IN2O5. Mole weight: 354.10.
Idoxuridine
Idoxuridine (5-Iodo-2-deoxyuridine, 5-IUdR, IdUrd) is an iodinated thymidine analogue that competitively inhibits phosphorylases. Idoxuridine can inhibit viral activity, particularly viral eye infections, including herpes simplex keratitis, by inhibiting DNA polymerase and affecting viral replication. Idoxuridine against feline herpesvirus has the IC 50 value of 4.3 μM [1]. Idoxuridine shows anti-orthopoxvirus activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5-Iodo-2-deoxyuridine; 5-IUdR; IdUrd. CAS No. 54-42-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0307.
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