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| Product | Description | |
|---|---|---|
| 5-methylaminomethyl-2-thiouridine | 5-methylaminomethyl-2-thiouridine, an indispensable compound in biomedicine, serves as a linchpin for scientific advancements. With widespread application in the exploration of antiviral agents and remedies for diverse ailments, this compound assumes a pivotal function. By enhancing the effectiveness of therapeutic interventions against viral infections, it unravels intricate mechanisms underlying drug action. Synonyms: 5-(Methylaminomethyl)-2-thiouridine; 2-Thio-5-(N-methylaminomethyl)uridine; 5-N-Methylaminomethyl-2-thiouridine; 2-Thio-5-methylaminomethyluridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-((methylamino)methyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; 5-[(Methylamino)methyl]-1-(β-D-ribofuranosyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone. Grades: ≥95%. CAS No. 32860-54-1. Molecular formula: C11H17N3O5S. Mole weight: 303.34. |  |
| geranylated 5-methylaminomethyl-2-thiouridine | Geranylated 5-methylaminomethyl-2-thiouridine is a modified nucleoside that has shown antiviral activity against HIV-1 and HCV. It has potential therapeutic applications in the treatment of viral infections. Research show that geranylated 5-methylaminomethyl-2-thiouridine afforded selective inhibition against HIV-1 Vif translation and HIV-1 replication. Molecular formula: C21H33N3O5S. Mole weight: 439.32. | |
| glutamate-tRNAGln ligase | When this enzyme acts on tRNAGlu, it catalyses the same reaction as EC 6.1.1.17, glutamate-tRNA ligase. It has, however, diminished discrimination, so that it can also form glutamyl-tRNAGln. This relaxation of specificity has been found to result from the absence of a loop in the tRNA that specifically recognizes the third position of the anticodon. This accounts for the ability of this enzyme in, for example, Bacillus subtilis, to recognize both tRNA1Gln (UUG anticodon) and tRNAGlu (UUC anticodon) but not tRNA2Gln (CUG anticodon). The ability of this enzyme to recognize both tRNAGlu and one of the tRNAGln isoacceptors derives from their sharing a major identity element, a hypermodified derivative of U34 (5-methylaminomethyl-2-thiouridine). The glutamyl-tRNAGln is not used in protein synthesis until it is converted by EC 6.3.5.7, glutaminyl-tRNA synthase (glutamine-hydrolysing), into glutaminyl-tRNAGln. Group: Enzymes. Synonyms: nondiscriminating glutamyl-tRNA synthetase. Enzyme Commission Number: EC 6.1.1.24. CAS No. 9068-76-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5656; glutamate-tRNAGln ligase; EC 6.1.1.24; 9068-76-2; nondiscriminating glutamyl-tRNA synthetase. Cat No: EXWM-5656. |  |
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