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5g Pack Size. Group: Biochemicals, Building Blocks, Research Organics & Inorganics. Formula: C18H22O4. CAS No. 500-38-9. Prepack ID 14957191-5g. Molecular Weight 302.36. See USA prepack pricing.
Nordihydroguaiaretic acid
Herbal Medicinal Products Standards. Uses: For analytical and research use. Group: Reagents. CAS No. 500-38-9. Pack Sizes: 50MG.
Nordihydroguaiaretic acid
NDGA (Nordihydroguaiaretic acid), also known as masoprocol, is a naturally occurring antioxidant dicatechol originally derived from the creosote bush Larrea divaricatta with antipromoter, anti-inflammatory, and antineoplastic activities. NDGA directly inhibits activation of two receptor tyrosine kinases (RTKs), the insulin-like growth factor receptor (IGF-1R) and the c-erbB2/HER2/neu receptor, resulting in decreased proliferation of susceptible tumor cell populations. This agent may induce apoptosis in susceptible tumor cell populations as a result of disruption of the actin cytoskeleton in association with the activation of stress activated protein kinases (SAPKs). In addition, NDGA inhibits arachidonic acid 5-lipoxygenase (5LOX), resulting in diminished synthesis of inflammatory mediators such as prostaglandins and leukotrines; it may prevent leukocyte infiltration into tissues and the release of reactive oxygen species and, at higher concentrations, may also inhibit cyclooxygenase. Synonyms: 4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol. Grades: > 98 %. CAS No. 500-38-9. Molecular formula: C18H22O4. Mole weight: 302.36.
Nordihydroguaiaretic acid
Nordihydroguaiaretic acid is a 5-lipoxygenase ( 5LOX ) ( IC 50 =8 μM) and tyrosine kinase inhibitor. Uses: Scientific research. Group: Natural products. Alternative Names: NDGA. CAS No. 500-38-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-N0198.