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| Product | Description | |
|---|---|---|
| ionomycin | ionomycin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 56092-81-0. Molecular Formula: C41H72O9. Mole Weight: 709.02. Catalog: APB56092810. |  |
| Ionomycin | Ionomycin is a selective calcium ionophore antibiotic isolated from Streptomyces species. Anti-Gram-positive activity. Synonyms: 10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-, (4R, 6S, 8S, 10Z, 12R, 14R, 16E, 18R, 19R, 20S, 21S)-; (4R, 6S, 8S, 10Z, 12R, 14R, 16E, 18R, 19R, 20S, 21S)-11, 19, 21-Trihydroxy-4, 6, 8, 12, 14, 18, 20-heptamethyl-22-[(2S, 2'R, 5S, 5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2, 5'-dimethyl[2, 2'-bifuran]-5-yl]-9-oxo-10, 16-docosadienoic acid; 10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[octahydro-5'-(1-hydroxyethyl)-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-, [2S-[2α[2'S*, 5'R*(S*)], 5β(4S*, 6R*, 8R*, 10Z, 12S*, 14S*, 16E, 18S*, 19S*, 20R*, 21R*)]]-; [2S-[2α[2'S*, 5'R*(S*)], 5β(4S*, 6R*, 8R*, 10Z, 12S*, 14S*, 16E, 18S*, 19S*, 20R*, 21R*)]]-11, 19, 21-Trihydroxy-4, 6, 8, 12, 14, 18, 20-heptamethyl-22-[octahydro-5'-(1-hydroxyethyl)-2, 5'-dimethyl[2, 2'-bifuran]-5-yl]-9-oxo-10, 16-docosadienoic acid; SQ 23377; EM 94. Grades: >98% by HPLC. CAS No. 56092-81-0. Molecular formula: C41H72O9. Mole weight: 709.00. |  |
| Ionomycin | Ionomycin (SQ23377) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin (SQ23377) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin also induces the activation of protein kinase C (PKC) [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: SQ23377. CAS No. 56092-81-0. Pack Sizes: 1 mg (14.1 mM * 100 μL in Ethanol); 5 mg (14.1 mM * 500 μL in Ethanol); 10 mg (14.1 mM * 1 mL in Ethanol). Product ID: HY-13434. |  |
| Ionomycin | Ionomycin was isolated from Streptomyces conglobatus as a potent antibiotic selective for Gram +ve bacteria. During the isolation it was recognised that ionomycin exhibits a very high affinity and selectivity for calcium ions suggesting the metabolite acts as a calcium ionophore. More recently, ionomycin has been used in cell biology as a universal calcium ionophore to explore the role of calcium regulation in the cell. Group: Biochemicals. Grades: Highly Purified. CAS No. 56092-81-0. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Ionomycin free acid | 1mg Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C41H72O9. CAS No. 56092-81-0. Prepack ID 22000466-1mg. Molecular Weight 709. See USA prepack pricing. |  |
| Ionomycin free acid | Ionomycin free acid. Group: Biochemicals. Grades: Purified. CAS No. 56092-81-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ionomycin (Free Acid) | Antibiotic. Potent and highly selective Ca2+ ionophore. Commonly used to modify intracellular calcium levels to study calcium transport across biological membranes and to calibrate fluorescent Ca2+ indicators. Ionomycin also transports Pb2+ and some other divalent cations, as well as several lanthanide series trivalent cations at efficiencies that are greater than or equal to those for Ca2+. Apoptosis inducer. Induces apoptotic neuronal degeneration in embryonic cortical neurons and cell cycle arrest at G1 phase and induces central demyelination. Used to stimulate the intracellular production of the cytokines, interferon, perforin, IL-2 and IL-4 usually in conjunction with PMA. ADAM10 agonist. Potent inducer of shedding CXCL16. TREK-1 channels inhibitor. PPARy ligand with a unique binding mode. Shows effective glucose-lowering activity in a mouse model of diabetes. Group: Biochemicals. Alternative Names: SQ 23377; EM 94; [2S-[2α[2S*, 5R*(S*)], 5 β(4S*, 6R*, 8R*, 10Z, 12S*, 14S*, 16E, 18S*, 19S*, 20R*, 21R*)]]-11, 19, 21-Trihydroxy-4, 6, 8, 12, 14, 18, 20-heptamethyl-22-[octahydro-5-(1-hydroxyethyl)-2, 5-dimethyl[2, 2-bifuran]-5-yl]-9-oxo-10, 16-docosadienoic Acid; [2S-[2α[2S*, 5R*(S*)], 5 β(4S*, 6R*, 8R*,. Grades: Highly Purified. CAS No. 56092-81-0. Pack Sizes: 1mg, 5mg. Molecular Formula: C??H??O?. US Biological Life Sciences. | Worldwide |
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