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Ionomycin calcium (SQ23377 calcium) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin calcium (SQ23377 calcium) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin calcium (SQ23377 calcium) also induces the activation of protein kinase C (PKC) [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: SQ23377 calcium. CAS No. 56092-82-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-13434A.
Ionomycin Calcium Salt
Antibiotic that acts as a potent and selective calcium ionophore; more effective than A23187. Ionomycin binds Ca2+ in the 7.0-9.5 pH range with the resulting complex exhibiting intense UV absorption. Ionomycin Calcium is a polyether antibiotic obtained from Streptomyces conglobatus by solvent extraction. It is different from other antibiotics of its class as it absorbs UV light at 300nm maximum. Gram-positive antibiotic. Group: Biochemicals. Alternative Names: Calcium Ionomycin; (4R, 6S, 8S, 10Z, 12R, 14R, 16E, 18R, 19R, 20S, 21S)-11, 19, 21-Trihydroxy-4, 6, 8, 12, 14, 18, 20-heptamethyl-22-[(2S, 2R, 5S, 5S)-octahydro-5-[(1R)-1-hydroxyethyl]-2, 5-dimethyl[2, 2-bifuran]-5-yl]-9-oxo-10, 16-Docosadienoic Acid Calcium Salt. Grades: Highly Purified. CAS No. 56092-82-1. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C41H70O9 Ca, Molecular Weight: 747.07. US Biological Life Sciences.
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Ionomycin Calcium Salt
The Calcium Salt of Ionomycin, a kind of polyether antibiotic, is a selective calcium ionophore obtained from Streptomyces conglobatus by solvent extraction. It is more effective than A23187 as a calcium ionophore. It is used to study the transport of calcium ions on biological membranes. It can induce apoptotic degeneration of embryonic cortical neurons. Synonyms: Calcium ionophore; Calcium Ionomycin; (4R, 6S, 8S, 10Z, 12R, 14R, 16E, 18R, 19R, 20S, 21S)-11, 19, 21-Trihydroxy-4, 6, 8, 12, 14, 18, 20-heptamethyl-22-[(2S, 2'R, 5S, 5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2, 5'-dimethyl[2, 2'-bifuran]-5-yl]-9-oxo-10, 16-Docosadienoic Acid Calcium Salt; 10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-, calcium salt (1:1), (4R, 6S, 8S, 10Z, 12R, 14R, 16E, 18R, 19R, 20S, 21S)-; Ionomycin, calcium salt (1:1). Grades: ≥98%. CAS No. 56092-82-1. Molecular formula: C41H70O9Ca. Mole weight: 747.07.
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