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| Product | Description | |
|---|---|---|
| Palbociclib | Palbociclib Inhibitor. Uses: Scientific use. Product Category: T1785. CAS No. 571190-30-2. |  |
| Palbociclib | Palbociclib (PD 0332991) is an orally active selective CDK4 and CDK6 inhibitor with IC 50 values of 11 and 16 nM, respectively. Palbociclib has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma [1] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD 0332991. CAS No. 571190-30-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-50767. |  |
| Palbociclib | Palbociclib (PD 0332991) is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma. Group: Inhibitors. Alternative Names: Palbociclib; 571190-30-2; PD0332991; Ibrance; PD-0332991; PD 0332991;UNII-G9ZF61LE7G;Palbociclib free base;Palbociclib-d8;6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one;PD-332991;571190-30-2 (free base); MFCD11840850; 6-ACETYL-8-CYCLOPENTYL-5-METHYL-2-[(5-PIPERAZIN-1-YLPYRIDIN-2-YL)AMINO]PYRIDO[2, 3-D]PYRIMIDIN-7(8H)-ONE; 6-Acetyl-8-cyclop. CAS No. 571190-30-2. Molecular formula: C24H29N7O2. Mole weight: 447.5g/mol. Purity: 0.9994. IUPACName: 6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one. Canonical SMILES: CC1=C (C (=O)N (C2=NC (=NC=C12)NC3=NC=C (C=C3)N4CCNCC4)C5CCCC5)C (=O)C. Catalog: ACM571190302. |  |
| Palbociclib, Free Base Salt, 99+% | PD 0332991 is a potent selective inhibitor of cyclin dependent kinases CDK4 and CDK6 with in vitro IC50 = 11 nM (CDK4) and 16 nM (CDK6). PD 0332991 induces G1 arrest in retinoblastoma (Rb)-positive tumor cells. Group: Biochemicals. Alternative Names: 6-acetyl-8-cyclopentyl-5-methyl-2- [ [5- (1-piperazinyl) -2-pyridinyl]amino]pyrido [2, 3-d]pyrimidin-7 (8H) -one 2-hydroxy-ethanesulfonic acid (1:1); PD0332991; Palbociclib; isethionate. Grades: Highly Purified. CAS No. 571190-30-2. Pack Sizes: 25mg, 50mg, 100mg. US Biological Life Sciences. |  Worldwide |
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