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| Product | Description | |
|---|---|---|
| 4, 5, 6, 7-Tetra bromobenzimidazole | 4, 5, 6, 7-Tetra bromobenzimidazole. Group: Biochemicals. Alternative Names: TBBz. Grades: Highly Purified. CAS No. 577779-57-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C7H2Br4N2. US Biological Life Sciences. |  Worldwide |
| 4,5,6,7-Tetrabromobenzimidazole | ,5,6,7-Tetrabromobenzimidazole is a selective, ATP-competitive inhibitor of CK2. Synonyms: Casein Kinase II Inhibitor XII; TBBz; 4,5,6,7-tetrabromo-1H-benzimidazole. Grades: ≥98%. CAS No. 577779-57-8. Molecular formula: C7H2Br4N2. Mole weight: 433.7. |  |
| Casein Kinase II Inhibitor XII, TBBz (4, 5, 6, 7-Tetra bromobenzimidazole, CYP24A1 inhibitor, TBBz, CK2 Inhibitor, TBBz) | A cell-permeable halogenated benzimidazole compound that acts as a selective and ATP competitive inhibitor of casein kinase II (CK2, Ki = 70nM for the active hetero-tetrameric form). However, its effect on free CK2a and CK2a' subunits is significantly reduced (Ki = 510 and 400nM, respectively). Reported to reduce viability and proliferation in HeLa, Jurkat, and HL-60 cells (at 25uM). Also shown to disrupt the promoter activity of CYP24A1 and down-regulates its endogenous and 1, 25-Vitamin D3 (1,25-D3)-induced expression in PC3 cells. Synergistically enhances the anti-tumor effect of 1, 25-D3 in a PC3 xenograft murine model. CAS No:577779-57-8. Group: Biochemicals. Grades: Highly Purified. CAS No. 577779-57-8. Pack Sizes: 20mg. Molecular Formula: C?H?Br?N?, Primary Target: CK2. US Biological Life Sciences. | Worldwide |
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