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Product
PI 3,4-K Inhibitor, PIK-93 (N- (5- (4-Chloro-3- ( ( (2-hydroxyethyl) amino) sulfonyl) phenyl) -4-methyl-2-thiazolyl) -acetamide) A cell-permeable phenylthiazole compound that acts as a potent, reversible and ATP-competitive PI 3,4-K family selective inhibitor (IC50=16, 19, 39 and 64nM for p110y, PI 4-KIIb, p110a and DNA-PK, respectively). Moderately inhibits p110d, PI 3-KC2b, hsVPS34, ATM, p110b and PI 4-KIIIa (IC50=0.120, 0.140, 0.320, 0.490, 0.590 and 1.1uM, respectively) with minimal inhibition towards a panel of 36-kinases (IC50>10uM). Shown to block ceramide transfer protein-mediated ceramide traffic between endoplasmic reticulum and Golgi in transfected COS-7 cells at 250nM. Group: Biochemicals. Grades: Highly Purified. CAS No. 593960-11-3. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 4
Worldwide
PIK-93 PIK-93 is a potent PI3K inhibitor. Synonyms: PIK-93; PIK 93; PIK93. Grades: 0.98. CAS No. 593960-11-3. Molecular formula: C14H16ClN3O4S2. Mole weight: 389.869. BOC Sciences 10

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