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| Product | Description | |
|---|---|---|
| 6-Diazo-5-oxo-L-nor-leucine | It is produced by the strain of Streptomyces ambofaciens. It has anti-tumor activity and is not suitable for clinical use due to excessive toxicity. Its N-acetyl (Duazomycin) also has anti-tumor effect. Uses: Antibiotics, antineoplastic. Synonyms: 6-Diazo-5-oxonorleucine; 6-diazo-5-oxo-L-norleucine; L-DON; (S)-2-Amino-6-diazo-5-oxocaproic acid; L-6-Diazo-5-oxonorleucine; DON; NSC 7365; L-DON; 2-Amino-6-diazo-5-oxohexanolic acid. Grades: ≥ 99% (Assay by titration). CAS No. 157-03-9. Molecular formula: C6H9N3O3. Mole weight: 171.15. |  |
| 6-Diazo-5-oxo-L-nor-Leucine | 6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L-6-Diazo-5-oxonorleucine; DON. CAS No. 157-03-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108357. |  |
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