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| Product | Description | |
|---|---|---|
| Prostaglandin J2 | Prostaglandin J2 (PGJ2), an endogenous metabolite of Prostaglandin D2 (PGD2; HY-101988), is a potent PGD2 receptor (DP) agonist with K i s of 0.9 nM and 6.6 nM for hDP and hCRTH2, respectively. Prostaglandin J2 stimulates intracellular cyclic AMP production with an EC 50 value of 1.2 nM. Prostaglandin J2 induces oxidative stress and neuronal apoptosis. Prostaglandin J2 induces the accumulation/aggregation of ubiquitinated (Ub) proteins. Prostaglandin J2 is highly neurotoxic and potentially contributes to many neurodegenerative conditions, including Alzheimer's (AD) and Parkinson's diseases (PD) [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: PGJ2. CAS No. 60203-57-8. Pack Sizes: 500 μg (14.95 mM * 100 μL in Methyl acetate). Product ID: HY-113366. |  |
| Prostaglandin J2 | Prostaglandin J2 (PGJ2) is a metabolite of PGD2, exhibiting antimitotic and antiproliferative effects. It inhibits platelet aggregation with IC50 value of 5-10 nM. Uses: Antineoplastic agents. Synonyms: PGJ2; 9-Deoxy-delta-9-prostaglandin D2; 9-Deoxy-delta-9-pgd2; (Z)-7-[(1S,5R)-5-[(E,3S)-3-hydroxyoct-1-enyl]-4-oxocyclopent-2-en-1-yl]hept-5-enoic acid. Grades: ≥95%. CAS No. 60203-57-8. Molecular formula: C20H30O4. Mole weight: 334.5. |  |
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