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GANT58 GANT 58 inhibits the hedgehog (Hh) signaling pathway downstream of SMO and SUFU causing GLI1 nuclear accumulation. Displays antiproliferative and antitumor activity in vivo. Synonyms: NSC 75503; GANT58; GANT-58; GANT 58; NSC-75503; NSC75503. Grades: 0.99. CAS No. 64048-12-0. Molecular formula: C24H16N4S. Mole weight: 392.47564. BOC Sciences 11
GANT 58 GANT 58. Group: Biochemicals. Grades: Purified. CAS No. 64048-12-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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GANT58 (2,3,4,5-Tetra(4-pyridyl)thiophene; NSC75503) Cell-permeable. Acts as a blocker of Hedgehog (Hh) pathway downstream of SMO and SUFU causing Gli1 nuclear accumulation. It also targets Gli-mediated gene transactivation (IC50 ~ 5uM in SAG-stimulated Shh-L2 cells) and displays anti-proliferative and antitumor activity in vivo. Group: Biochemicals. Alternative Names: 2,3,4,5-Tetra(4-pyridyl)thiophene; NSC75503. Grades: Highly Purified. CAS No. 64048-12-0. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 1
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