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| Product | Description | |
|---|---|---|
| 4-Demethylepipodophyllotoxin | 4-Demethylepipodophyllotoxin - Product ID: NST-10-86. Category: Polyphenols. Purity: 98%. Test method: HPLC. CAS No. 6559-91-7. Pack Sizes: 5g, 10g, 25g, 50g. Appearance: White Powder. Molecular formula: C21H20O8. Mole weight: 400.38. Storage: +2 +8 °C. |  |
| 4'-Demethylepipodophyllotoxin | 4'-Demethylepipodophyllotoxin (4'-DMEP) is a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer drugs; a potent inhibitor of microtubule assembly.IC50 Value: 0.31uM(EC5 0in HL60 cell, MTT assay, 48h); 0.37uM(EC50 in HepG2 cell, MTT assay, 48h) Target: microtubulein vitro: 4-TMP-DMEP showed strong cytotoxicity activity against the above-mentioned five tumor cell lines. The EC50s of 4-TMP-DMEP against these tumor cell lines ranged from 0.24 to 0.11 μM, which were 0.29 to 3618 times lower than that of DMEP.in vivo: Treatment of animals with DMEP (until the end of the experiment), 30 min before TPA treatment, significantly reduced the tumor incidence, tumor volume and the conversion efficiency of papillomas to squamous cell carcinomas. The tumor formation and growth was also delayed by DMEP pre-treatment. Group: Inhibitors. Alternative Names: 4-Domethylpodophyllotoxin, 4'-demethyl-epi-podophyllotoxin. CAS No. 6559-91-7. Molecular formula: C21H20O8. Mole weight: 400.38. Appearance: Powder. Purity: 0.98. IUPACName: (5S,5aR,8aR,9R)-5-hydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one. Canonical SMILES: COC1=CC (=CC (=C1O)OC)[C@H]2[C@@H]3[C@H] (COC3=O)[C@@H] (C4=CC5=C (C=C24)OCO5)O. Density: 1.446±0.06 g/ml. Catalog: ACM6559917. |  |
| 4'-Demethylepipodophyllotoxin | 4'-Demethylepipodophyllotoxin (4'-DMEP) is an intermediate compound that inhibits microtubule assembly. Uses: Scientific research. Group: Natural products. Alternative Names: 4'-O-demethylepipodophyllotoxin; 4'-DMEP. CAS No. 6559-91-7. Pack Sizes: 500 mg; 1 g. Product ID: HY-17435. |  |
| 4'-De methyl epipodophyllotoxin | 4'-De methyl epipodophyllotoxin. Group: Biochemicals. Alternative Names: 4'-DMEP. Grades: Highly Purified. CAS No. 6559-91-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C21H20O8. US Biological Life Sciences. |  Worldwide |
| De methyl podophyllotoxin, 4'- | De methyl podophyllotoxin, 4'-. Group: Biochemicals. CAS No. 6559-91-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Etoposide Impurity E | Etoposide Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (5R,5aR,8aR,9S)-9-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,5a,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one. CAS No. 6559-91-7. Molecular Formula: C21H20O8. Mole Weight: 400.38. Catalog: APB6559917. |  |
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