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| Product | Description | |
|---|---|---|
| Dihydrochelerythrine | Dihydrochelerythrine is a natural compound isolated from Corydalis yanhusuo; has antifungal activity.IC50 value:Target:in vitro: Dihydrochelerythrine showed the highest antifungal activity against B. cinerea Pers, with 98.32% mycelial growth inhibition at 50 μg/mL. Dihydrochelerythrine inhibited spore germination in vitro in a concentration-dependent manner. Dihydrochelerythrine appeared to be less cytotoxic since the viability of cells exposed to 20 microM dihydrochelerythrine for 24h was reduced only to 53%. A dose-dependent induction of apoptosis and necrosis by chelerythrine and dihydrochelerythrine was confirmed by annexin V/propidium iodide dual staining flow cytometry. Dihydrochelerythrine (4) exhibited strong activity against methicillin-resistant Staphylococcus aureus SK1 and moderate activity against Escherichia coli TISTR 780 with MIC values of 8 and 16 μg/mL, respectively. Group: Inhibitors. Alternative Names: 12,13-Dihydro-1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridine. CAS No. 6880-91-7. Molecular formula: C21H19NO4. Mole weight: 349.4. Appearance: Solid. Purity: 95%+. Canonical SMILES: CN1C (C2=CC (OCO3)=C3C=C2C=C4)=C4C5=CC=C (OC)C (OC)=C5C1. Catalog: ACM6880917. |  |
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