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| Product | Description | |
|---|---|---|
| BX795 | BX795 Inhibitor. Uses: Scientific use. Product Category: T1830. CAS No. 702675-74-9. |  |
| BX795 | BX795 is a potent and selective inhibitor of PDK1, with an IC50 of 6 nM. BX795 is also a potent and relatively specific inhibitor of TBK1 and IKK?, with an IC50 of 6 and 41 nM, respectively. BX795 blocks phosphorylation of S6K1, Akt, PKC?, and GSK3?, and has lower selectivity over PKA, PKC, c-Kit, GSK3? etc. BX795 modulates autophagy[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 702675-74-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10514. |  |
| BX 795 | BX 795. Group: Biochemicals. Grades: Purified. CAS No. 702675-74-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| BX-795 | 3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a serine-threonine kinase that phosphorylates and activates a range of other kinases, including PKB, PKA, and certain isoforms of PKC. BX795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, which is 140- and 1600-fold more selective than PKA and PKC. It is also a potent and relatively specific inhibitor of TBK1 with IC50 of 6 nM and IKK? with IC50 of 41 nM. Synonyms: BX 795; BX795. Grade: ≥98%. CAS No. 702675-74-9. Molecular formula: C23H26IN7O2S. Mole weight: 591.47. |  |
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