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PHA-793887 Quick inquiry Where to buy Suppliers range | PHA-793887 is an inhibitor of multiple cyclin dependent kinases (CDK) with activity against CDK2, CDK1 and CDK4. Although toxicity was acceptable at initial dose levels, PHA-793887 was poorly tolerated at doses ≥44 mg/m2. The most frequent events across all dose levels were gastrointestinal or nervous system events. PHA-793887 induces severe, dose-related hepatic toxicity, which was not predicted by pre-clinical models and currently precludes its further clinical development. Synonyms: PHA 793887; PHA793887. Grades: >98%. CAS No. 718630-59-2. Molecular formula: C19H31N5O2. Mole weight: 361.48. |