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| Product | Description | |
|---|---|---|
| Ciglitazone | Ciglitazone is a potent and selective PPARγ agonist ( EC 50 =3 μM). Ciglitazone inhibits proliferation and differentiation of th17 cells. Ciglitazone is a hypoglycemic agent orally active in the obese-hyperglycemic animal models. Ciglitazone induces apoptosis accompanied by activation of p38 MAPK and nuclear translocation of apoptosis inducing factor (AIF) in opossum kidney (OK) renal epithelial cells [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ADD-3878; U-63287. CAS No. 74772-77-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W011220. |  |
| Ciglitazone | Ciglitazone is a selective agonist at peroxisome proliferator-activated receptor γ (PPARγ) with an EC50 value of 3 μM in vitro. It is at least 33-fold selective over PPARα and &delta. It shows antihyperglycemic activity in genetically obese C57 B1/6 ob/ob mice and is used as an antihyperglycemic agent. Uses: Hypoglycemic agents. Synonyms: ADD 3878; ADD-3878; ADD3878; Ciglitazona; U 63287; U-63287; U63287; ADD 3878; ADD-3878; ADD3878; (+/-) -5-[4- (1-methylcyclohexylmethoxy) benzyl]thiazolidine-2, 4-dione; ADD-3878; 5-[[4-[ (1-Methylcyclohexyl) methoxy]phenyl]methyl]-2, 4-thiazolidinedione. Grades: ≥99% by HPLC. CAS No. 74772-77-3. Molecular formula: C18H23NO3S. Mole weight: 333.44. |  |
| Ciglitazone | Selective PPARgamma agonist (EC50=3uM). Hypoglycemic agent. Angiogenesis inhibitor. Anti-inflammatory. Apoptosis inducer. Group: Biochemicals. Grades: Highly Purified. CAS No. 74772-77-3. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C18H23NO3S. US Biological Life Sciences. |  Worldwide |
| Ciglitazone ( (±) -5- [4- (1- methyl cyclohexylmethoxy) benzyl] thiazolidine-2, 4-dione, ADD-3878) | An antidiabetic drug. A thiazolidinedione (TDZ) type of antihyperglycemic agent. It displays antihyperglycemic activity in genetically obese C57 Bl/6 ob/ob mice and is a selective PPARγ agonist (EC50 = 3uM). Group: Biochemicals. Alternative Names: (±) -5- [4- (1- methyl cyclohexylmethoxy) benzyl] thiazolidine-2, 4-dione. Grades: Highly Purified. CAS No. 74772-77-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
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