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| Product | Description | |
|---|---|---|
| 8-Chloroadenosine | 8-Chloroadenosine (8-Cl-Ado), a unique ribonucleoside analog, depletes endogenous ATP that subsequently induces the phosphorylation and activation of AMPK. 8-Chloroadenosine induces autophagic cell death. 8-Chloroadenosine effectively inhibited in vivo tumor growth in mice [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 8-Cl-Ado. CAS No. 34408-14-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-103400. |  |
| 8-Chloroadenosine | 8-Chloroadenosine. Group: Biochemicals. Grades: Purified. CAS No. 34408-14-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| 8-Chloroadenosine | 8-Chloroadenosine is an analog of adenosine. It is metabolized in vivo to 8-Chloro-ATP. It depletes ATP and inhibits tumor growth in hematological malignancies. It also inhibits tumor growth in lung and breast cancer cell lines. It incorporates into RNA during transcription and inhibits RNA synthesis. It mitotics catastrophe and induces G2/M cell cycle arrest in A549 and H1299 cells. It is a useful research chemical and has cytotoxicity effects. Synonyms: 6-Amino-8-chloropurine riboside; 8-Cl-Ado; 8-Chloro-adenosine; (2R,3R,4S,5R)-2-(6-amino-8-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-Chloro-D-adenosine. Grades: ≥98% by HPLC. CAS No. 34408-14-5. Molecular formula: C10H12ClN5O4. Mole weight: 301.69. |  |
| 8-Chloroadenosine 3?,5?-cyclic-monophosphate | ?85%. Group: Fluorescence/luminescence spectroscopy. |  |
| 8-Chloroadenosine 3',5'-cyclic monophosphate | 8-Chloroadenosine 3',5'-cyclic monophosphate. Group: Biochemicals. Alternative Names: 8-Cl-cAMP. Grades: Highly Purified. CAS No. 41941-56-4. Pack Sizes: 1mg, 2mg, 4mg. Molecular Formula: C10H11ClN5O6P. US Biological Life Sciences. | Worldwide |
| 8-Chloroadenosine 3',5'-Cyclic Monophosphate | 8-Chloroadenosine 3',5'-Cyclic Monophosphate is a cAMP analog with high selectivity for PKA I. Used in anti-cancer treatments. Uses: Antineoplastic agents. Synonyms: 8-Chloro-cAMP; 8-Chloro-cyclic AMP; 8-Chloroadenosine 3',5'-Cyclic Monophosphate; 8-Chloroadenosine 3',5'-Cyclic Phosphate; Adenazole; NSC 284751; NSC 614491; Tocladesine. Grades: 95%. CAS No. 41941-56-4. Molecular formula: C10H11ClN5O6P. Mole weight: 363.65. | |
| 8-Chloroadenosine 3',5'-cyclic monophosphate dihydrate | 8-Chloroadenosine 3',5'-cyclic monophosphate dihydrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 41941-56-4. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C10H11ClN5O6P·2H2O. US Biological Life Sciences. | Worldwide |
| 8-Chloroadenosine 3',5'-cyclic monophosphate dihydrate | 8-Chloroadenosine 3',5'-cyclic monophosphate dihydrate is a key compound used in biomedical research. It acts as an adenosine receptor agonist, exhibiting therapeutic potential in the treatment of various diseases including cancer, inflammation, and neurodegenerative disorders. Its unique properties make it an essential tool for studying nucleotide signaling pathways and developing targeted therapies to combat these conditions. Molecular formula: C10H11ClN5O6P·2H2O. Mole weight: 399.69. | |
| 8-Chloroinosine | A major metabolite of 8-Chloroadenosine. Synonyms: 8-Chloro-inosine; 8-Cl-I; (2R,3R,4S,5R)-2-(8-Chloro-6-hydroxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-Chloro-D-inosine; 9H-Purin-6-ol, 8-chloro-9-β-D-ribofuranosyl-. Grades: ≥95%. CAS No. 116285-77-9. Molecular formula: C10H11ClN4O5. Mole weight: 302.67. | |
| 8-Chloroinosine (8-Chloro-inosine, 8-Cl-I) | A major metabolite of 8-Chloroadenosine. Group: Biochemicals. Alternative Names: 8-Chloro-inosine; 8-Cl-I. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 8-Cl-5'-AMP | 8-Cl-5'-AMP is a potential metabolite of 8-chloroadenosine-3',5'-cyclic monophosphate. Synonyms: 8- Chloroadenosine- 5'- O- monophosphate, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 37676-40-7. Molecular formula: C10H13ClN5O7P (free acid). Mole weight: 381.7 (free acid). | |
| 8-Cl-Ino | 8-Cl-Ino is the potential metabolite of 8-chloro cyclic AMP and 8-chloroadenosine. Synonyms: 8- Chloroinosine. Grades: ≥ 98% by HPLC. CAS No. 116286-77-9. Molecular formula: C10H11ClN4O6. Mole weight: 302.7. | |
| Adenosine,8-chloro-,cyclic 3',5'-[hydrogen(S)-phosphorothioate](9ci) | Adenosine,8-chloro-,cyclic 3',5'-[hydrogen(S)-phosphorothioate](9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT;ADENOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE, 8-CHLORO-, SP-ISOMER, SODIUM SALT;SP-8-CL-CAMPS, NA;SP-8-CL-CAMPS SODIUM SALT;8-chloroadenosine-3',5'-cyclicmonophosphorothioate;8-chl. Product Category: Heterocyclic Organic Compound. CAS No. 142754-28-7. Molecular formula: C10H11ClN5O5PS. Mole weight: 401.7. Purity: 0.96. IUPACName: cyclohexane-1,2-diamine; platinum(2+); 3,4,5-trihydroxy-1-oxidocyclohexane-1-carboxylate. Density: g/cm³. Product ID: ACM142754287. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 8-Cl-Ado | 8-Cl-Ado is a cytotoxic metabolite of 8-chloro cyclic AMP. Synonyms: 8- Chloroadenosine. Grades: ≥ 98% by HPLC. CAS No. 34408-14-6. Molecular formula: C10H12ClN6O4. Mole weight: 301.7. | |
| 8-Cl-ADP | 8-Cl-ADP is a metabolite of 8-Cl-cAMP and 8-Cl-adenosine and a precursor of 8-modified ADP derivatives. Synonyms: 8- Chloroadenosine- 5'- O- diphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 185341-69-9. Molecular formula: C10H14ClN5O10P2 (free acid). Mole weight: 461.7 (free acid). | |
| 8-Cl-ATP | 8-Cl-ATP is a corresponding triphosphate form for research on 8-chloro cAMP and 8-Cl-adenosine. Synonyms: 8- Chloroadenosine- 5'- triphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 185341-71-3. Molecular formula: C10H15ClN5O13P3 (free acid). Mole weight: 541.6 (free acid). | |
| 8-Cl-cAMP | 8-Cl-cAMP is a selective cAMP analogue preferring protein kinase A type I. 8-Cl-cAMP has already been in several clinical trials to identify its inhibitory effect of growth and differentiation in cultured cancer cell lines. Synonyms: 8- Chloroadenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 124705-03-9. Molecular formula: C10H10ClN5O6P · Na. Mole weight: 385.6. | |
| 8-Cl-cAMP-AM | 8-Cl-cAMP-AM is a precursor of 8-Cl-cAMP, the PKA activator. The polar active analogue is released after the metabolism of 8-Cl-cAMP-AM by esterases. Synonyms: 8- Chloroadenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grades: ≥ 97% by HPLC for mixture of isomers. Molecular formula: C13H15ClN5O8P. Mole weight: 435.7. | |
| Rp-8-Cl-cAMPS | Rp-8-Cl-cAMPS is a selective and competitive inhibitor of protein kinase A (cAMP antagonist) preferring type I of protein kinase A. It inhibits mammalian cyclic nucleotide-dependent phosphodiesterases. Synonyms: 8- Chloroadenosine- 3', 5'- monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 142754-27-6. Molecular formula: C10H10ClN5O5PS · Na. Mole weight: 401.7. | |
| Sp-8-Cl-cAMPS | Sp-8-Cl-cAMPS is a resistant stimulator of protein kinase A, the cAMP agonist. Compared with 8-Cl-cAMP, it has the increased lipophilic and membrane-permeant properties. Synonyms: 8- Chloroadenosine- 3', 5'- monophosphorothioate, Sp- isomer. Grades: ≥ 99% by HPLC. CAS No. 142754-28-7. Molecular formula: C10H10ClN5O5PS · Na. Mole weight: 401.7. | |
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