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| Product | Description | |
|---|---|---|
| 8-OH-DPAT | 8-OH-DPAT (8-Hydroxy-DPAT) is an agonist that has selectivity for 5-HT1A receptor (pIC50 = 8.19). It was subsequently found to be a serotonin reuptake inhibitor and a 5-HT7 receptor agonist as well. Studies showed that it exhibited antidepressant, anxiolytic and other properties. Uses: Serotonin receptor agonists. Synonyms: 8-HYDROXY-2-(DI-n-PROPYLAMINO)TETRALIN; 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol; CHEMBL56; Ro-31-8220 in solution; 8-Hydroxy-DPAT. Grades: 99.03 %. CAS No. 78950-78-4. Molecular formula: C16H25NO. Mole weight: 247.38. |  |
| 8-OH-DPAT | 8-OH-DPAT is a potent and selective 5-HT agonist, with a pIC 50 of 8.19 for 5-HT1A and a K i of 466 nM for 5-HT7; 8-OH-DPAT weakly binds to 5-HT1B (pIC 50 , 5.42), 5-HT (pIC 50 <5). Uses: Scientific research. Group: Signaling pathways. Alternative Names: 8-Hydroxy-DPAT. CAS No. 78950-78-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112061. |  |
| 8-OH-DPAT hydrobromide | 8-OH-DPAT (8-Hydroxy-DPAT) hydrobromide is a potent and selective 5-HT 1A agonist with a pIC 50 of 8.19. 8-OH-DPAT hydrobromide has selectivity of almost 1000 fold for a subtype of the 5-HT 1 binding site [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 8-Hydroxy-DPAT hydrobromide. CAS No. 76135-31-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15688. | |
| WAY-100635 Maleate (5-HT1A Serotonis Receptor Antagonist, WAY-100635 Maleate, WAY 100635, WAY100635) | A selective 5-HT1A receptor antagonist (pKi = 7.9-9.2). WAY-100635 has been reported to have good inhibitory action centrally and peripherally (1mg/kg dose in rats) but has low intrinsic effects, making it a silent 5-HT1A receptor antagonist. WAY-100635 displaced specific binding of the 5-HT1A radioligand, [3H]8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)tetralin), to rat hippocampal membranes with a pIC50 of 8.87. This represented a greater than 100-fold selectivity relative to binding at other 5-HT receptor subtypes and major neurotransmitter receptor, reuptake and ion channel sites. WAY-100635 has been used in a variety of vertebrate species in vivo and in vitro. Group: Biochemicals. Grades: Highly Purified. CAS No. 634908-75-1. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
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