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| Product | Description | |
|---|---|---|
| Phenoxodiol | Phenoxodiol (Idronoxil), a synthetic analog of Genestein, activates the mitochondrial caspase system, inhibits XIAP (an apoptosis inhibitor), and sensitizes the cancer cells to Fas-mediated apoptosis. Phenoxodiol also inhibits DNA topoisomerase II by stabilizing the cleavable complex. Phenoxodiol induces cell cycle arrest in the G1/S phase of the cell cycle and upregulates p21WAF1 via a p53 independent manner. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DEHYDROEQUOL;7,4-DIHYDROXYISOFLAV-3-ENE;PHENOXODIOL;Haginin E;Idronoxil;3-(4-Hydroxyphenyl)-2H-1-benzopyran-7-ol;PhenoxodiolHaginin EIdronoxil;2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-. Product Category: Inhibitors. Appearance: Solid. CAS No. 81267-65-4. Molecular formula: C15H12O3. Mole weight: 240.25. Purity: 0.9976. Canonical SMILES: OC1=CC=C2C=C(C3=CC=C(O)C=C3)COC2=C1. Product ID: ACM81267654. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Phenoxodiol | Phenoxodiol is a synthetic flavonoid derivative. Phenoxodiol activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis (XIAP), and disrupts FLICE inhibitory protein (FLIP) expression, resulting in tumor cell apoptosis. This agent also inhibits DNA topoisomerase II by stabilizing the cleavable complex, thereby preventing DNA replication and resulting in tumor cell death. Synonyms: Idronoxil; Dehydroequol; Haginin E; NV-06; NV06; NV 06; 2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-; 3-(4-Hydroxyphenyl)-2H-1-benzopyran-7-ol; 7,4'-Dihydroxyisoflav-3-ene; 7-hydroxy-3-hydroxyphenyl-1H-benzopyran. Grades: ≥98%. CAS No. 81267-65-4. Molecular formula: C15H12O3. Mole weight: 240.25. |  |
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