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| Product | Description | |
|---|---|---|
| Rottlerin - CAS 82-08-6 | A cell-permeable and reversible protein kinase C inhibitor that exhibits greater selectivity for PKC? (IC?? = 3-6 μM) and PKC?. Group: Fluorescence/luminescence spectroscopy. |  |
| Rottlerin | Rottlerin, a natural product purified from Mallotus Philippinensis, is a specific PKC inhibitor, with IC50 values for PKC? of 3-6 ?M, PKC?,?,? of 30-42 ?M, PKC?,?,? of 80-100 ?M. Rottlerin acts as a direct mitochondrial uncoupler, and stimulates autophagy by targeting a signaling cascade upstream of mTORC1. Rottlerin induces apoptosis via caspase 3 activation[1][2][3]. Rottlerin inhibits HIV-1 integration and Rabies virus (RABV) infection[4][5]. Uses: Scientific research. Group: Natural products. Alternative Names: Mallotoxin; NSC 56346; NSC 94525. CAS No. 82-08-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-18980. |  |
| Rottlerin | Rottlerin, a principal phenolic compound of the Kamala plant Mallotus philippinensis, originally reported to inhibit PKC isoforms, especially PKCδ and CAM-KIII. Recently, it has been shown to inhibit a wide range of protein kinases, and most potently to inhibit PRAK and MAPKAP-K2 (IC50 values are 1.9 and 5 μM respectively). Uses: Enzyme inhibitors. Synonyms: 3'-[(8-Cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)methyl]-2',4',6'-trihydroxy-5'-methylacetophenone. Grades: ≥98% (HPLC). CAS No. 82-08-6. Molecular formula: C30H28O8. Mole weight: 516.55. |  |
| Rottlerin | Rottlerin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MALLOTOXIN;3'-[(8-CINNAMOYL-5,7-DIHYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-6-YL)METHYL]-2',4',6'-TRIHYDROXY-5'-METHYLACETOPHENONE;4',6'-trihydroxy-5'-methyl-methyl)-2;acetophenone,3'-((8-cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2h-1-benzopyran-6-yl);kamalin;ROTT. Product Category: Heterocyclic Organic Compound. Appearance: orange to brown powder. CAS No. 82-08-6. Molecular formula: C30H28O8. Mole weight: 516.54. Product ID: ACM82086. Alfa Chemistry ISO 9001:2015 Certified. |  |
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