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| Product | Description | |
|---|---|---|
| Nefazodone HCl | Nefazodone hydrochloride is a selective serotonin 5-HT2 receptor antagonist. It is used as an antidepressant that shows no cardiac toxicity or anticholinergic activity common with tricyclic antidepressants. It is a phenylpiperazin derivative, whose structure is similar to that of some known antidepressants. It was developed by Bristol-Myers Squibb. Uses: Nefazodone hydrochloride is used as an antidepressant that shows no cardiac toxicity or anticholinergic activity common with tricyclic antidepressants. Synonyms: BMY 13754; BMY13754; BMY-13754; Dutonin; Nefazodone HCl; Rulivan; MJ 13754 1; MJ-13754-1; MJ137541. 3H-1,2,4-Triazol-3-one, 2-3-4-(3-chlorophenyl)-1-piperazinylpropyl-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-, monohydrochloride;Nefazodone HCl;BMY-13754;MJ-13754-1;2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl- 2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one hydrochloride;2,4-Dihydro-2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-5-ethyl-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one hydrochloride; Serzone; Dutonin; Menfazona. Grades: 95%. CAS No. 82752-99-6. Molecular formula: C25H33Cl2N5O2. Mole weight: 506.46. |  |
| Nefazodone hydrochloride | Nefazodone hydrochloride (BMY-13754) is a potent and selective 5HT2A ( K i =5.8 nM) antagonist with moderate inhibition of 5-HT and noradrenaline uptake ( IC 50 of 290 and 300 nM, respectively). Nefazodone hydrochloride is a phenylpiperazine antidepressant with less alpha-adrenergic blocking activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMY-13754; MJ-13754-1. CAS No. 82752-99-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B1396. |  |
| Nefazodone hydrochloride | Nefazodone hydrochloride. CAS No: 82752-99-6 |  Sarchem Laboratories New Jersey NJ |
| Nefazodone hydrochloride | Nefazodone hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 82752-99-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Nefazodone Hydrochloride (5-HT2A Serotonin Receptor Antagonist, Nefazodone, BMY-13754, MJ-13754-1, Serzone) | A potent 5-HT2A receptor antagonist (Kd = 26nM), with moderate affinity for the alpha1-adrenergic receptor (Kd = 48nM) and 5-HT1A receptor (Kd = 80nM). Originally developed as a clinical antidepressant but discontinued in 2004, nefazodone (Serzone) still remains a specific inhibitor of certain serotonergic pathways. Nefazodone also has been reported to induce mitochondrial dysfunction. Group: Biochemicals. Grades: Highly Purified. CAS No. 82752-99-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
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