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| Product | Description | |
|---|---|---|
| HM-30181 hydrochloride | HM30181 is a P-glycoprotein (P-gp) inhibitor developed to enhance the oral bioavailability of P-gp substrate drugs. HM30181 showed the highest potency among several MDR1 inhibitors with IC50 value of 0.63nM. HM30181 is currently under Phase I trials. Uses: Enhance the oral bioavailability of p-gp substrate drugs. Synonyms: HM-30181 hydrochloride; HM 30181 hydrochloride; HM30181 hydrochloride; N-(2-(2-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-2H-tetrazol-5-yl)-4,5-dimethoxyphenyl)-4-oxo-4H-chromene-2-carboxamide hydrochloride. Grades: 98%. CAS No. 849675-88-3. Molecular formula: C38H37ClN6O7. Mole weight: 725.20. |  |
| HM-30181 mesylate | HM30181 is a P-glycoprotein (P-gp) inhibitor developed to enhance the oral bioavailability of P-gp substrate drugs. HM30181 showed the highest potency among several MDR1 inhibitors with IC50 value of 0.63nM. HM30181 is currently under Phase I trials. Uses: Enhance the oral bioavailability of p-gp substrate drugs. Synonyms: HM-30181 mesylate; HM 30181 mesylate; HM30181 mesylate; N-(2-(2-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-2H-tetrazol-5-yl)-4,5-dimethoxyphenyl)-4-oxo-4H-chromene-2-carboxamide methanesulfonate;849675-88-3 (HM30181 HCl salt);49675-66-7 (HM30181 Free base). Grades: 98%. CAS No. 849675-87-2. Molecular formula: C39H40N6O10S. Mole weight: 784.84. | |
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