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AUZ 454 AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 8.2 nM. AUZ 454 (K03861) inhibits CDK2 activity by competing with binding of activating cyclins. Uses: Scientific research. Group: Signaling pathways. Alternative Names: K03861. CAS No. 853299-07-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15004. MedChemExpress MCE
K03861 K03861 is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely. Synonyms: AUZ 454; K 03861; K-03861; Urea, N-[4-[(2-amino-4-pyrimidinyl)oxy]phenyl]-N'-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-; 1-[4-[(2-Amino-4-pyrimidinyl)oxy]phenyl]-3-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]urea. Grades: 98%. CAS No. 853299-07-7. Molecular formula: C24H26F3N7O2. Mole weight: 501.50. BOC Sciences 8

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