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Product | Description | |
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PK 11195 Quick inquiry Where to buy Suppliers range | PK 11195 has high affinity for the peripheral benzodiazepine receptor (PBR, TSPO) without binding to other known neurotransmitter receptors. It can also inhibit the human constitutive androstane receptor (hCAR). In Mar 2006, Preclinical for Cancer in United Kingdom was discontinued. Uses: Anticancer. Synonyms: PK11195; PK-11195; PK 11195. 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide; N-Methyl-N-(1-methylpropyl)-1-(2-chlorophenyl)isoquinoline-3-carboxamide; RP 52028; RP52028; RP-52028. Grades: 98%. CAS No. 85532-75-8. Molecular formula: C21H21ClN2O. Mole weight: 352.86. | |
PK 11195 Quick inquiry Where to buy Suppliers range | Cell-permeable. A Selective peripheral benzodiazepine antagonist. Enhances apoptosis and induces mitochondria cytochrome c release. Inhibits insulin secretion induced by glucose. Also displays anticancer activity. Group: Biochemicals. Alternative Names: 1- (2-Chloro phenyl ) -N- methyl -N- (1- methyl propyl ) -3-isoquinolinecarboxamid e . Grades: Highly Purified. CAS No. 85532-75-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
PK11195 Quick inquiry Where to buy Suppliers range | An isoquinoline carboxamide that acts as a potent ligand for peripheral bezodiazepine receptor (Kd = 20nM). Exhibits anti-inflammatory properties. Binds to monocytes and following lesioning its binding up-regulated in brain macrophages and activated microglia. Shown to enhance the susceptibility of cells to apoptosis induction by DNA damaging agents and can reverse the suppression of apoptosis by Bcl-2. Serves as a ligand of the outer membrane translocator protein and reduces mitochondrial transmembrane potential within 30 minutes of exposure (100uM).CAS Number:85532-75-8. Group: Biochemicals. Grades: Highly Purified. CAS No. 85532-75-8. Pack Sizes: 10mg. Molecular Formula: C??H??ClN?O. US Biological Life Sciences. | Worldwide |
PK 11195 (1- (2-Chloro phenyl ) -N- methyl -N- (1- methyl propyl ) -3-isoquinolinecarboxamid e ) Quick inquiry Where to buy Suppliers range | Selective peripheral benzodiazepine antagonist. Apoptosis enhancer. Glucose-induced insulin secretion inhibitor. Induces mitochondria cytochrome c release. Anticancer compound. Antiproliferative. Pharmacological tool in autophagy. Group: Biochemicals. Grades: Highly Purified. CAS No. 85532-75-8. Pack Sizes: 10mg. Molecular Formula: C21H21ClN2O, Molecular Weight: 352.9. US Biological Life Sciences. | Worldwide |
(R)-PK11195 Quick inquiry Where to buy Suppliers range | PK 11195, 85532-75-8, PK11195, 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide, PK-11195, RP 52028, UNII-YNF83VN1RL, YNF83VN1RL, 85340-56-3, BRN 4264456, DTXSID7041097, CHEBI:73290, 3-Isoquinolinecarboxamide, 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-, N-butan-2-yl-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide, N-sec-butyl-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide, PK11195,(R)-(-)-, C21H21ClN2O, N-(butan-2-yl)-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide, N-(sec-Butyl)-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide, (R)-PK11195, SMR000058427, SR-01000076240, 205934-46-9, Biomol-NT_000287, D03NOO, D0VN4K, Lopac0_000198, Interferon alfa (IFN-alpha), MLS000028483, MLS006010699, CHEMBL15313, SCHEMBL117124, BPBio1_001278, CHEMBL481537, GTPL8703, DTXCID5021097, BDBM22032, HMS2234C05, HMS3260H17, HMS3266H15, HMS3372J02, HMS3411O10, HMS3675O10, HMS3870J13, EX-A2448, Tox21_300620, Tox21_500198, HB0922, PDSP1_000637, PDSP2_000632, AKOS024458600, CCG-204293, LP00198, SDCCGSBI-0050186.P002, NCGC00015205-03, NCGC00015205-04, NCGC00015205-05, NCGC00015205-06, NCGC00015205-07, NCGC00015205-08, NCGC00015205-14, NCGC00024720-02, NCGC00024720-03, NCGC00024720-04, NCGC00254354-01, NCGC00260883-01, [3H]PK 11195, BM166506, HY-19567, LS-85394, MS-25479, RP-52028, CAS-85532-75-8, CS-0015789, EU-0100198, FT-0724157, PK-11195; RP-52028, C 0424, E98630, 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl), Q7119490, SR-01000076240-1, SR-01000076240-3, BRD-A41451487-001-01-3, BRD-A41451487-001-04-7, 1-(2-Chloro-phenyl)-isoquinoline-3-carboxylic acid sec-butyl-methyl-amide, N-METHYL-N-(1-METHYLPROPYL)-1-(2-CHLOROPHENYL)ISOQUINOLINE-3-CARBOXAMIDE, (R)PK-11195, N-[(2r)-Butan-2-Yl]-1-(2-Chlorophenyl)-N-Methylisoquinoline-3-Carboxamide, 1-(2-Chlorophenyl)-N-methyl-N-[(1R)-1-methylpropyl]-3-isoquinolinecarboxamide, (R)-PK11195, 205934-46-9, D0O6JQ, CHEMBL416715, SCHEMBL3126094, BDBM50054139, LS-85395, Q27464457, (r)-n-methyl-n-(1-methylpropyl)-1-(2-chlorophenyl)isoquinoline-3-carboxamide, (R)1-(2-Chloro-phenyl)-isoquinoline-3-carboxylic acid sec-butyl-methyl-amide. | |
(R,S)-PK11195 Quick inquiry Where to buy Suppliers range | (R,S) PK11195. CAS No. 85532-75-8. |