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Product | Description | |
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H 1152 dihydrochloride Quick inquiry Where to buy Suppliers range | H 1152 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 871543-07-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
H-1152 Dihydrochloride Quick inquiry Where to buy Suppliers range | H-1152 Dihydrochloride is a cell-permeable isoquinolinesulfonamide compound that acts as a highly specific, potent, and ATP-competitive inhibitor of G-protein Rho-associated kinase with a Ki value of 1.6 nM, but poor inhibitor of other serine/threonine kinases. It inhibits sulprostone-induced contractions in guinea pig aorta (IC50 = 190 nM) and displays proerectile effects in rats. It selectively blocks lysophosphatidic acid-induced, but not PDBu-induced, phosphorylation of myristoylated alanine-rich C kinase substrate MARCKS (IC50=2.5nM) in NT-2 cells. Synonyms: (S) - (+) -2-Methyl-1-[ (4-methyl-5-isoquinolynyl) sulfonyl]homopiperazine Dihydrochloride;5-[[(2S)-Hexahydro-2-Methyl-1H-1,4-diazepin-1-yl]sulfonyl]-4-Methylisoquinoline dihydrochloride;4-methyl-5-[[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinoline dihydrochloride. Grades: >98 %. CAS No. 871543-07-6. Molecular formula: C16H23Cl2N3O2S. Mole weight: 392.34. | |
H-1152 Dihydrochloride Quick inquiry Where to buy Suppliers range | H-1152 Dihydrochloride. Group: Biochemicals. Alternative Names: 5-[[(2S)-Hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-4-methylisoquinoline. Grades: Highly Purified. CAS No. 871543-07-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C16H23Cl2N3O2S. US Biological Life Sciences. | Worldwide |
H-1152 Dihydrochloride Quick inquiry Where to buy Suppliers range | H-1152 Dihydrochloride. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. CAS No. 871543-07-6. IUPAC Name: 4-methyl-5-[[(2S)-2-methyl-1, 4-diazepan-1-yl]sulfonyl]isoquinoline; dihydrochloride. Molecular formula: C16H21N3O2S.2ClH. Mole weight: 392.34. Catalog: APS871543076. SMILES: Cl. Cl. C[C@H]1CNCCCN1S (=O) (=O)c2cccc3cncc (C)c23. Format: Neat. | |
H1152, DIHYDROCHLORIDE Quick inquiry Where to buy Suppliers range | H1152, DIHYDROCHLORIDE. CAS No. 871543-07-6. |