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CK 1827452 CK-1827452 is a diaryl urea compound that increases cardiac myosin ATPase activity in a dose-dependent manner that is selective for cardiac myosin over non-cardiac myosins. It promotes myosin cross-bridge formation, increasing the duration and amount of myocyte contraction without affecting intracellular calcium or cAMP. It has been shown to increase cardiac efficiency in clinical studies of patients with chronic heart failure. Group: Biochemicals. Alternative Names: Methyl 4- [ [2-Fluoro-3- [N'- (6-methylpyridin-3-yl) ureido] phenyl] methyl] piperazine-1-carboxylate; 4- [ [2-Fluoro-3- [ [ [ (6-methyl-3-pyridinyl) amino] carbonyl] amino] phenyl] methyl] -1-piperazinecarboxylic Acid Methyl Ester; Omecamtiv Mecarbil. Grades: Highly Purified. CAS No. 873697-71-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??FN?O?, Molecular Weight: 401.43. US Biological Life Sciences. USBiological 3
Worldwide
Omecamtiv mecarbil Omecamtiv mecarbil (CK-1827452) is a selective cardiac myosin activator. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CK-1827452. CAS No. 873697-71-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14233. MedChemExpress MCE
Omecamtiv mecarbil Omecamtiv mecarbil is a cardiac-specific myosin activator with an EC50 of 0.6 μM. Synonyms: Omecamtiv mecarbil; CK1827452; CK 1827452; CK1827452. Grades: >98%. CAS No. 873697-71-3. Molecular formula: C20H24FN5O3. Mole weight: 401.43. BOC Sciences 9

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