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Product | Description | |
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CK 1827452 Quick inquiry Where to buy Suppliers range | CK-1827452 is a diaryl urea compound that increases cardiac myosin ATPase activity in a dose-dependent manner that is selective for cardiac myosin over non-cardiac myosins. It promotes myosin cross-bridge formation, increasing the duration and amount of myocyte contraction without affecting intracellular calcium or cAMP. It has been shown to increase cardiac efficiency in clinical studies of patients with chronic heart failure. Group: Biochemicals. Alternative Names: Methyl 4- [ [2-Fluoro-3- [N'- (6-methylpyridin-3-yl) ureido] phenyl] methyl] piperazine-1-carboxylate; 4- [ [2-Fluoro-3- [ [ [ (6-methyl-3-pyridinyl) amino] carbonyl] amino] phenyl] methyl] -1-piperazinecarboxylic Acid Methyl Ester; Omecamtiv Mecarbil. Grades: Highly Purified. CAS No. 873697-71-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??FN?O?, Molecular Weight: 401.43. US Biological Life Sciences. | Worldwide |
Omecamtiv mecarbil Quick inquiry Where to buy Suppliers range | Omecamtiv mecarbil is a cardiac-specific myosin activator with an EC50 of 0.6 μM. Synonyms: Omecamtiv mecarbil; CK1827452; CK 1827452; CK1827452. Grades: >98%. CAS No. 873697-71-3. Molecular formula: C20H24FN5O3. Mole weight: 401.43. |