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| Product | Description | |
|---|---|---|
| KG5 | KG5 is an orally active dual PDGFRβ and B-Raf allosteric inhibitor. KG5 also inhibits Flt3 , KIT and c-Raf. KG5 has anticancer, antiangiogenic activities [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 877874-85-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15198. |  |
| KG 5 | KG 5 is a B-Raf allosteric and PDGFRβ inhibitor. It inhibits FLT3, KIT and c-Raf. It arrests cells in prometaphase and inhibits growth of renal and pancreatic tumors in mice. It also inhibits angiogenesis in a mouse angiogenesis model and disrupts blood vessel formation in zebrafish embryos. It is orally available. Synonyms: KG-5; KG 5; KG5; 2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine; 2-Methylsulfanyl-6-[4-[3-[3-(trifluoromethyl)anilino]-1H-1,2,4-triazol-5-yl]phenoxy]pyrimidin-4-amine. Grades: ≥98% by HPLC. CAS No. 877874-85-6. Molecular formula: C20H16F3N7OS. Mole weight: 459.45. |  |
| KG-5 | KG-5 is an orally available PDGFRß and B-Raf allosteric inhibitor. Uses: Designed for use in research and industrial production. Additional or Alternative Names: KG-5; KG 5; KG5. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 877874-85-6. Molecular formula: C20H16F3N7OS. Mole weight: 459.45. Purity: >98%. IUPACName: 2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine. Canonical SMILES: NC1=NC(SC)=NC(OC2=CC=C(C3=NNC(NC4=CC=CC(C(F)(F)F)=C4)=N3)C=C2)=C1. Product ID: ACM877874856. Alfa Chemistry ISO 9001:2015 Certified. Categories: KG 51. |  |
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